Identification of Inhibitory Activities of Dietary Flavonoids against URAT1, a Renal Urate Re-Absorber: In Vitro Screening and Fractional Approach Focused on Rooibos Leaves
Yu Toyoda(University of Tokyo Hospital), Hiroshi Suzuki(Obihiro University of Agriculture and Veterinary Medicine), Tappei Takada(University of Tokyo Hospital), Ami Ota-Kontani(Sapporo Holdings (Japan)), Hiroki Saito(University of Tokyo Hospital), Hiroshi Hirata(Yamaguchi University), Youichi Tsuchiya(Kyushu University)
Cited by 18
Related Papers
Decreased extra-renal urate excretion is a common cause of hyperuricemia
|Nature Communications|2012|703
Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population
|Science Translational Medicine|2009|438
Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes
|Annals of the Rheumatic Diseases|2015|185
GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes
|Annals of the Rheumatic Diseases|2016|177
ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload
|Scientific Reports|2014|164