piRBase: integrating piRNA annotation in all aspects

Jiajia Wang(Chinese Academy of Sciences), Yirong Shi(Chinese Academy of Sciences), Honghong Zhou(Chinese Academy of Sciences), Peng Zhang(Chinese Academy of Sciences), Tingrui Song(Chinese Academy of Sciences), Zhiye Ying(Sichuan University), Haopeng Yu(Sichuan University), Yanyan Li(Chinese Academy of Sciences), Yi Zhao(Chinese Academy of Sciences), Xiaoxi Zeng(Sichuan University), Shunmin He(Chinese Academy of Sciences), Runsheng Chen(Chinese Academy of Sciences)
Nucleic Acids Research
October 13, 2021
10.1093/nar/gkab1012
Cited by 102Open Access
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Abstract

Piwi-interacting RNAs are a type of small noncoding RNA that have various functions. piRBase is a manually curated resource focused on assisting piRNA functional analysis. piRBase release v3.0 is committed to providing more comprehensive piRNA related information. The latest release covers >181 million unique piRNA sequences, including 440 datasets from 44 species. More disease-related piRNAs and piRNA targets have been collected and displayed. The regulatory relationships between piRNAs and targets have been visualized. In addition to the reuse and expansion of the content in the previous version, the latest version has additional new content, including gold standard piRNA sets, piRNA clusters, piRNA variants, splicing-junction piRNAs, and piRNA expression data. In addition, the entire web interface has been redesigned to provide a better experience for users. piRBase release v3.0 is free to access, browse, search, and download at http://bigdata.ibp.ac.cn/piRBase.

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