Targeted Covalent Inhibition of Small CTD Phosphatase 1 to Promote the Degradation of the REST Transcription Factor in Human Cells
Brenda P. Medellin(The University of Texas at Austin), Yan Zhang(Fujian Agriculture and Forestry University), Seema Irani(Memorial Sloan Kettering Cancer Center), Wendy L. Matthews(The University of Texas at Austin), Haoyi Wu(The University of Texas MD Anderson Cancer Center), Wanjie Yang(The University of Texas at Austin), Srihari Konduri(University of California San Diego), Jiajun Dong(Purdue University West Lafayette), Dionico Siegel(University of California San Diego)
Cited by 11
Related Papers
Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation
|Molecular Cell|2021|265
Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
|Molecular Cell|2021|128
Immune checkpoint blockade resistance in lung cancer: emerging mechanisms and therapeutic opportunities
|Trends in Pharmacological Sciences|2024|53
Autotaxin suppresses cytotoxic T cells via LPAR5 to promote anti–PD-1 resistance in non–small cell lung cancer
|Journal of Clinical Investigation|2023|24