GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity

Sabine Heitzeneder(Stanford University), Kristopher R. Bosse(Children's Hospital of Philadelphia), Zhongyu Zhu(National Cancer Institute), Doncho V. Zhelev(University of Pittsburgh), Robbie G. Majzner(Stanford University), Molly Radosevich(Stanford University), Shaurya Dhingra(Stanford University), Elena Sotillo(Stanford University), Samantha N. Buongervino(Children's Hospital of Philadelphia), Guillem Pascual‐Pasto(Children's Hospital of Philadelphia), Emily Garrigan(Children's Hospital of Philadelphia), Peng Xu(Stanford University), Jing Huang(Stanford University), Benjamin Salzer(Christian Doppler Laboratory for Thermoelectricity), Alberto Delaidelli, Swetha Raman(Hospital for Sick Children), Hong Cui(Hospital for Sick Children), Benjamin Martinez(Hospital for Sick Children), Scott J. Bornheimer(BD Biosciences (United States)), Bita Sahaf(Stanford University), Anya S. Alag(Stanford University), Irfete S. Fetahu(University of Pittsburgh), Martin Hasselblatt(University Hospital Münster), Kevin R. Parker(Stanford University), Hima Anbunathan(Stanford University), Jennifer Hwang(National Cancer Institute), Min Huang(Stanford University), Kathleen M. Sakamoto(Stanford University), Norman J. Lacayo(Stanford University), Dorota D. Klysz(Stanford University), Johanna Theruvath(Stanford University), José G. Vilches-Moure(Stanford University), Ansuman T. Satpathy(Stanford University), Howard Y. Chang(Howard Hughes Medical Institute), Manfred Lehner(Christian Doppler Laboratory for Thermoelectricity), Sabine Taschner‐Mandl(St Anna Children's Hospital), Jean-Phillipe Julien(University of Toronto), Poul H. Sorensen, Dimiter S. Dimitrov(University of Pittsburgh), John M. Maris(Children's Hospital of Philadelphia), Crystal L. Mackall(Parker Institute for Cancer Immunotherapy)
Cancer Cell
December 30, 2021
Cited by 160Open Access
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