Ensembl 2022

Fiona Cunningham(European Bioinformatics Institute), James E. Allen(European Bioinformatics Institute), Jamie Allen(European Bioinformatics Institute), Jorge Álvarez-Jarreta(European Bioinformatics Institute), M Ridwan Amode(European Bioinformatics Institute), Irina M. Armean(European Bioinformatics Institute), Olanrewaju Austine-Orimoloye(European Bioinformatics Institute), Andrey G Azov(European Bioinformatics Institute), If Barnes(European Bioinformatics Institute), Ruth Bennett(European Bioinformatics Institute), Andrew Berry(European Bioinformatics Institute), Jyothish Bhai(European Bioinformatics Institute), Alexandra Bignell(European Bioinformatics Institute), Konstantinos Billis(European Bioinformatics Institute), Sanjay Boddu(European Bioinformatics Institute), Lucy Brooks(European Bioinformatics Institute), Mehrnaz Charkhchi(European Bioinformatics Institute), Carla Cummins(European Bioinformatics Institute), Luca Da Rin Fioretto(European Bioinformatics Institute), Claire Davidson(European Bioinformatics Institute), Kamalkumar Dodiya(European Bioinformatics Institute), Sarah Donaldson(European Bioinformatics Institute), Bilal El Houdaigui(European Bioinformatics Institute), Tamara El Naboulsi(European Bioinformatics Institute), Reham Fatima(European Bioinformatics Institute), Carlos García Girón(European Bioinformatics Institute), Thiago A. L. Genez(European Bioinformatics Institute), Jose Gonzalez Martinez(European Bioinformatics Institute), Cristina Guijarro-Clarke(European Bioinformatics Institute), Arthur W. Gymer(European Bioinformatics Institute), Matthew P. Hardy(European Bioinformatics Institute), Zoe Hollis(European Bioinformatics Institute), Thibaut Hourlier(European Bioinformatics Institute), Toby Hunt(European Bioinformatics Institute), Thomas Juettemann(European Bioinformatics Institute), Vinay Kaikala(European Bioinformatics Institute), Mike Kay(European Bioinformatics Institute), Ilias Lavidas(European Bioinformatics Institute), Anh Tuấn Lê(European Bioinformatics Institute), Diana Lemos(European Bioinformatics Institute), José Carlos Marugán(European Bioinformatics Institute), Shamika Mohanan(European Bioinformatics Institute), Aleena Mushtaq(European Bioinformatics Institute), Marc Naven(European Bioinformatics Institute), Denye Ogeh(European Bioinformatics Institute), Anne Parker(European Bioinformatics Institute), Andrew Parton(European Bioinformatics Institute), Malcolm Perry(European Bioinformatics Institute), Ivana Piližota(European Bioinformatics Institute), Irina Prosovetskaia(European Bioinformatics Institute), Manoj Pandian Sakthivel(European Bioinformatics Institute), Ahamed Imran Abdul Salam(European Bioinformatics Institute), Bianca M. Schmitt(European Bioinformatics Institute), Helen Schuilenburg(European Bioinformatics Institute), Dan Sheppard(European Bioinformatics Institute), José G Pérez-Silva(European Bioinformatics Institute), William Stark(European Bioinformatics Institute), Emily Steed(European Bioinformatics Institute), Kyösti Sutinen(European Bioinformatics Institute), Ranjit Sukumaran(European Bioinformatics Institute), Dulika Sumathipala(European Bioinformatics Institute), Marie‐Marthe Suner(European Bioinformatics Institute), Michał Szpak(European Bioinformatics Institute), Anja Thormann(European Bioinformatics Institute), Francesca Floriana Tricomi(European Bioinformatics Institute), David Urbina-Gómez(European Bioinformatics Institute), Andres Veidenberg(European Bioinformatics Institute), Thomas Walsh(European Bioinformatics Institute), Brandon Walts(European Bioinformatics Institute), Natalie L Willhoft(European Bioinformatics Institute), Andrea Winterbottom(European Bioinformatics Institute), Elizabeth Wass(European Bioinformatics Institute), Marc Chakiachvili(European Bioinformatics Institute), Bethany Flint(European Bioinformatics Institute), Adam Frankish(European Bioinformatics Institute), Stefano Giorgetti(European Bioinformatics Institute), Leanne Haggerty(European Bioinformatics Institute), Sarah Hunt(European Bioinformatics Institute), Garth R IIsley(European Bioinformatics Institute), Jane Loveland(European Bioinformatics Institute), Fergal J. Martin(European Bioinformatics Institute), Benjamin Moore(European Bioinformatics Institute), Jonathan M. Mudge(European Bioinformatics Institute), Matthieu Muffato(European Bioinformatics Institute), Emily Perry(European Bioinformatics Institute), Magali Ruffier(European Bioinformatics Institute), John Tate(European Bioinformatics Institute), David Thybert(European Bioinformatics Institute), Stephen J. Trevanion(European Bioinformatics Institute), Sarah Dyer(European Bioinformatics Institute), Peter W. Harrison(European Bioinformatics Institute), Kevin Howe(European Bioinformatics Institute), Andrew Yates(European Bioinformatics Institute), Daniel R. Zerbino(European Bioinformatics Institute), Paul Flicek(European Bioinformatics Institute)
Nucleic Acids Research
October 19, 2021
10.1093/nar/gkab1049
Cited by 2,159Open Access
Full Text

Abstract

Ensembl (https://www.ensembl.org) is unique in its flexible infrastructure for access to genomic data and annotation. It has been designed to efficiently deliver annotation at scale for all eukaryotic life, and it also provides deep comprehensive annotation for key species. Genomes representing a greater diversity of species are increasingly being sequenced. In response, we have focussed our recent efforts on expediting the annotation of new assemblies. Here, we report the release of the greatest annual number of newly annotated genomes in the history of Ensembl via our dedicated Ensembl Rapid Release platform (http://rapid.ensembl.org). We have also developed a new method to generate comparative analyses at scale for these assemblies and, for the first time, we have annotated non-vertebrate eukaryotes. Meanwhile, we continually improve, extend and update the annotation for our high-value reference vertebrate genomes and report the details here. We have a range of specific software tools for specific tasks, such as the Ensembl Variant Effect Predictor (VEP) and the newly developed interface for the Variant Recoder. All Ensembl data, software and tools are freely available for download and are accessible programmatically.

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