Accumulation of Intracellular L-Lactate and Irreversible Disruption of Mitochondrial Membrane Potential upon Dual Inhibition of Oxphos and Lactate Transporter MCT-1 Induce Synthetic Lethality in T-ALL Via Mitochondrial Exhaustion
Natalia Baran(The University of Texas MD Anderson Cancer Center), Marina Konopleva(Albert Einstein College of Medicine), Meghan Collins(The University of Texas at Austin), Gheath Alatrash(Mayo Clinic), Pratip K. Bhattacharya(The University of Texas MD Anderson Cancer Center), Zhihong Zeng(The University of Texas MD Anderson Cancer Center), Cassandra L. Ramage(The University of Texas MD Anderson Cancer Center), Joseph R. Marszalek(The University of Texas MD Anderson Cancer Center), Yogesh Dhungana(St. Jude Children's Research Hospital), Jose Enriquez Ortiz(The University of Texas MD Anderson Cancer Center), Alessia Lodi(The University of Texas at Austin), Jiyang Yu(Columbia University Irving Medical Center), Eric Davis(The University of Texas MD Anderson Cancer Center), Shraddha Patel(The University of Texas MD Anderson Cancer Center), Connie C. Weng(The University of Texas MD Anderson Cancer Center), Anna Skwarska(Albert Einstein College of Medicine), Kala Hayes(The University of Texas MD Anderson Cancer Center), Stefano Tiziani(Dell Children's Medical Center of Central Texas)
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