Neoadjuvant PD-1 blockade with toripalimab, with or without celecoxib, in mismatch repair-deficient or microsatellite instability-high, locally advanced, colorectal cancer (PICC): a single-centre, parallel-group, non-comparative, randomised, phase 2 trial

Huabin Hu; Liang Kang; Jianwei Zhang; Zehua Wu; Hui Wang; Meijin Huang; Ping Lan; Xiaojian Wu; Chao Wang; Wuteng Cao; Jiancong Hu; Yan Huang; Liang Huang; Huaiming Wang; Lishuo Shi; Yue Cai; Cailu Shen; Jiayu Ling; Xiaoyu Xie; Yonghua Cai; Xiaowen He; Ruoxu Dou; Jiaming Zhou; Tenghui Ma; Xingwei Zhang; Shuangling Luo; Weihao Deng; Li Ling; Hao Liu; Yanhong Deng

doi:10.1016/s2468-1253(21)00348-4

Neoadjuvant PD-1 blockade with toripalimab, with or without celecoxib, in mismatch repair-deficient or microsatellite instability-high, locally advanced, colorectal cancer (PICC): a single-centre, parallel-group, non-comparative, randomised, phase 2 trial

Huabin Hu(Sun Yat-sen University), Liang Kang(Sixth Affiliated Hospital of Sun Yat-sen University), Jianwei Zhang(Sixth Affiliated Hospital of Sun Yat-sen University), Zehua Wu(Sun Yat-sen University), Hui Wang(Sun Yat-sen University), Meijin Huang(Sun Yat-sen University), Ping Lan(Sixth Affiliated Hospital of Sun Yat-sen University), Xiaojian Wu(Sixth Affiliated Hospital of Sun Yat-sen University), Chao Wang(Sixth Affiliated Hospital of Sun Yat-sen University), Wuteng Cao(Sun Yat-sen University), Jiancong Hu(Sun Yat-sen University), Yan Huang(Sun Yat-sen University), Liang Huang(Sun Yat-sen University), Huaiming Wang(Sixth Affiliated Hospital of Sun Yat-sen University), Lishuo Shi(Sixth Affiliated Hospital of Sun Yat-sen University), Yue Cai(Sixth Affiliated Hospital of Sun Yat-sen University), Cailu Shen(Sixth Affiliated Hospital of Sun Yat-sen University), Jiayu Ling(Sixth Affiliated Hospital of Sun Yat-sen University), Xiaoyu Xie(Sun Yat-sen University), Yonghua Cai(Sixth Affiliated Hospital of Sun Yat-sen University), Xiaowen He(Sixth Affiliated Hospital of Sun Yat-sen University), Ruoxu Dou(Sixth Affiliated Hospital of Sun Yat-sen University), Jiaming Zhou(Sun Yat-sen University), Tenghui Ma(Sun Yat-sen University), Xingwei Zhang(Sun Yat-sen University), Shuangling Luo(Sun Yat-sen University), Weihao Deng(Sixth Affiliated Hospital of Sun Yat-sen University), Li Ling(Sun Yat-sen University), Hao Liu(Rutgers Cancer Institute of New Jersey), Yanhong Deng(Sun Yat-sen University)

The Lancet. Gastroenterology & hepatology

October 22, 2021

10.1016/s2468-1253(21)00348-4

Cited by 293

Abstract

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