Cognitive disorders in patients with chronic kidney disease: specificities of clinical assessment
Marion Pépin(Inserm), Ana Carina Ferreira(Hospital Curry Cabral), Mustafa Arıcı(Hacettepe University), Maie Bachman(Tallinn University of Technology), Michelangela Barbieri(University of Campania "Luigi Vanvitelli"), Inga Arūnė Bumblytė(Lithuanian University of Health Sciences), Sol Carriazo(Hospital Universitario Fundación Jiménez Díaz), Pilar Delgado(Universitat Autònoma de Barcelona), Liliana Gârneaţă(Carol Davila University of Medicine and Pharmacy), Konstantinos Giannakou(European University Cyprus), Olivier Godefroy(Laboratoire de neurosciences fonctionnelles et pathologies), Tomasz Grodzicki(Jagiellonian University), Aleksandra Klimkowicz‐Mrowiec(Jagiellonian University), Justina Kurganaite(Lithuanian University of Health Sciences), Sophie Liabeuf(Centre Hospitalier Universitaire Amiens-Picardie), Carmen-Antonia Mocanu(Carol Davila University of Medicine and Pharmacy), Giuseppe Paolisso(University of Campania "Luigi Vanvitelli"), Goce Spasovski(Ss. Cyril and Methodius University in Skopje), Evgueniy Vazelov, Davide Viggiano(University of Campania "Luigi Vanvitelli"), Carmine Zoccali(Renal Research Institute), Ziad A. Massy(Inserm), Andrzej Więcek(Medical University of Silesia), CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target), Giovambattista Capasso, Alexandre Andrade(Tallinn University of Technology), Maie Bachmann(Lithuanian University of Health Sciences), Inga Arūnė Bumblytė(Lithuanian University of Health Sciences), Adrian Covic(Universitat Autònoma de Barcelona), Pilar Delgado(Universitat Autònoma de Barcelona), Nicole Endlich, Andreas Engvig, Denis Fouque, Casper Franssen, Sebastian Frische(Carol Davila University of Medicine and Pharmacy), Liliana Gârneaţă(Carol Davila University of Medicine and Pharmacy), Loreto Gesualdo(European University Cyprus), Konstantinos Giannakou(European University Cyprus), Dimitrios Goumenos, Ayşe Tuğba Kartal, Laila-Yasmin Mani, Hans-Peter Marti, Christopher Mayer, Rikke Nielsen, Vesna Pešić, Merita Rroji, Giorgos K. Sakkas(Ss. Cyril and Methodius University in Skopje), Goce Spasovski(Ss. Cyril and Methodius University in Skopje), Kate Stevens, Evgueniy Vazelov(University of Campania "Luigi Vanvitelli"), Davide Viggiano(University of Campania "Luigi Vanvitelli"), Lefteris C. Zacharia(Hospital Curry Cabral), Ana Carina Ferreira(Hospital Curry Cabral), Jolanta Małyszko, Ewout J. Hoorn, Andreja Figurek, Robert J. Unwin, Carsten A. Wagner, Christoph Wanner, Annette Bruchfeld(Inserm), Marion Pépin(Inserm), Andrzej Więcek(Medical University of Silesia), Dorothea Nitsch, Ivo Fridolin, Gaye Hafez, María José Soler Romeo(University of Campania "Luigi Vanvitelli"), Michelangela Barbieri(University of Campania "Luigi Vanvitelli"), Bojan Batinić, Laura Carrasco(Hospital Universitario Fundación Jiménez Díaz), Sol Carriazo(Hospital Universitario Fundación Jiménez Díaz), Ron T. Gansevoort, Gianvito Martino, Francesco Mattace‐Raso, Ionuţ Nistor, Alberto Ortíz(University of Campania "Luigi Vanvitelli"), Giuseppe Paolisso(University of Campania "Luigi Vanvitelli"), Daiva Rastenytė, Gabriel Ştefan, Gioacchino Tedeschi(Inserm), Ziad A. Massy(Inserm), Boris Bikbov, Karlhans Endlich(Laboratoire de neurosciences fonctionnelles et pathologies), Olivier Godefroy(Laboratoire de neurosciences fonctionnelles et pathologies), Jean‐Marc Chillon, Anastassia Kossioni(Lithuanian University of Health Sciences), Justina Kurganaite(Lithuanian University of Health Sciences), Norberto Perico(University of Campania "Luigi Vanvitelli"), Giuseppe Remuzzi(Jagiellonian University), Tomasz Grodzicki(Jagiellonian University), Francesco Trepiccione(Renal Research Institute), Carmine Zoccali(Renal Research Institute), Mustafa Arıcı(Hacettepe University), Peter J. Blankestijn, Kai‐Uwe Eckardt, Danilo Fliser, Eugenio Gutiérrez Jiménez, Maximilian König, Ivan Rychlík(University of Campania "Luigi Vanvitelli"), Michela Deleidi, György Reusz
Cited by 73Open Access
Abstract
Neurocognitive disorders are frequent among chronic kidney disease (CKD) patients. Identifying and characterizing cognitive impairment (CI) can help to assess the ability of adherence to CKD risk reduction strategy, identify potentially reversible causes of cognitive decline, modify pharmacotherapy, educate the patient and caregiver and provide appropriate patient and caregiver support. Numerous factors are associated with the development and progression of CI in CKD patients and various conditions can influence the results of cognitive assessment in these patients. Here we review clinical warning signs that should lead to cognitive screening; conditions frequent in CKD at risk to interfere with cognitive testing or performance, including specificities of cognitive assessment in dialysis patients or after kidney transplantation; and available tests for screening and observed cognitive patterns in CKD patients.
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