IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies
Matthias Friedrich(Nuffield Orthopaedic Centre), Michael B. Brenner(Brigham and Women's Hospital), Sarah McCuaig(Nuffield Orthopaedic Centre), Hannah Sharpe(University of Oxford), Matthew Jackson(King's College London), Kévin Rue-Albrecht(Hammersmith Hospital), Samuel J. Bullers(Nuffield Orthopaedic Centre), Rahul Ravindran(John Radcliffe Hospital), Ruchi Tandon(Translational Health Science and Technology Institute), Dharshan Sathananthan(John Radcliffe Hospital), Kara G. Lassen(Roche (Switzerland)), Mark Coles(University of Oxford), Ilya Korsunsky(Broad Institute), Kevin Wei(Brigham and Women's Hospital), Raphael Sanches Peres(Universidade de São Paulo), Elizabeth H. Mann(Nuffield Orthopaedic Centre), Alessandra Geremia(John Radcliffe Hospital), Zoe Christoforidou(John Radcliffe Hospital), Christopher D. Buckley(Queen Elizabeth Hospital Birmingham), Moustafa Attar(Centre for Human Genetics), Holm H. Uhlig(University of Oxford), Mathilde Pohin(Nuffield Orthopaedic Centre), Tom Thomas(Nuffield Orthopaedic Centre), Simon Travis(University of Oxford), Francesca Barone(Celldex Therapeutics (United States)), Gerald F. Watts(Royal Perth Hospital), Soumya Raychaudhuri(Broad Institute), Alistair Easton(Manchester Academic Health Science Centre), Stephen N. Sansom(University of Oxford), Elena Collantes(John Radcliffe Hospital), Andreas P. Frei(Roche (Switzerland)), Lloyd Thomas(John Radcliffe Hospital)
Cited by 289
Related Papers
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
|Nature|2012|4.8k
The landscape of somatic copy-number alteration across human cancers
|Nature|2010|4.1k
Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel
|European Heart Journal|2017|3.8k
Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society
|European Heart Journal|2013|2.7k
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
|Nature Genetics|2010|2.6k