Intermittent High Glucose Elevates Nuclear Localization of EZH2 to Cause H3K27me3-Dependent Repression of KLF2 Leading to Endothelial Inflammation
Sumukh Thakar(Birla Institute of Technology and Science, Pilani), Syamantak Majumder(St. Michael's Hospital)
Cited by 36
Related Papers
Shifts in podocyte histone H3K27me3 regulate mouse and human glomerular disease
|Journal of Clinical Investigation|2017|123
Dysregulated expression but redundant function of the long non-coding RNA HOTAIR in diabetic kidney disease
|Diabetologia|2019|55
S-nitrosylation of EZH2 alters PRC2 assembly, methyltransferase activity, and EZH2 stability to maintain endothelial homeostasis
|Nature Communications|2025|4
Regulation of shelterin proteins TERF2IP and TRF2 by H3K4me3-p65 axis drives hyperglycemia dependent endothelial senescence
|bioRxiv (Cold Spring Harbor Laboratory)|2023|0
S-nitrosylation of EZH2 at C329 and C700 interplay with PRC2 complex assembly, methyltransferase activity, and EZH2 stability to regulate endothelial functions
|bioRxiv (Cold Spring Harbor Laboratory)|2024|0