Deletion of the A137R Gene from the Pandemic Strain of African Swine Fever Virus Attenuates the Strain and Offers Protection against the Virulent Pandemic Virus

Douglas P. Gladue(Plum Island Animal Disease Center), Elizabeth Ramírez-Medina(Plum Island Animal Disease Center), Elizabeth A. Vuono(University of Wisconsin–Madison), Ediane Silva(Plum Island Animal Disease Center), Ayushi Rai(Oak Ridge Associated Universities), Sarah Pruitt(Plum Island Animal Disease Center), Nallely Espinoza(Plum Island Animal Disease Center), Lauro Velázquez-Salinas(Plum Island Animal Disease Center), Manuel V. Borca(Plum Island Animal Disease Center)
Journal of Virology
August 18, 2021
Cited by 136Open Access
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Abstract

), demonstrating its potential as a vaccine candidate. Therefore, ASFV-G-ΔA137R is a novel experimental ASF vaccine protecting pigs from the epidemiologically relevant ASFV Georgia isolate.


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