High-purity production and precise editing of DNA base editing ribonucleoproteins

Hyeon‐Ki Jang(Hanyang University), Dong Hyun Jo(Seoul National University), Seu-Na Lee(Korea University), Chang Sik Cho(Seoul National University Hospital), You Kyeong Jeong(Hanyang University), Youngri Jung(Hanyang University), Jihyeon Yu(Hanyang University), Jeong Hun Kim(Seoul National University), Jae‐Sung Woo(Korea University), Sangsu Bae(Hanyang University)
Science Advances
August 27, 2021
10.1126/sciadv.abg2661
Cited by 85Open Access
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Abstract

Cytosine and adenine base editor ribonucleoproteins show precise base editing with reduced DNA and RNA off-target effects.

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