OpenABM-Covid19—An agent-based model for non-pharmaceutical interventions against COVID-19 including contact tracing

Robert Hinch(University of Oxford), William J. M. Probert(University of Oxford), Anel Nurtay(University of Oxford), Michelle Kendall(University of Warwick), Chris Wymant(University of Oxford), Matthew Hall(University of Oxford), Katrina Lythgoe(University of Oxford), Ana Bulas Cruz(University of Oxford), Lele Zhao(University of Oxford), Andrea Stewart(University of Oxford), Luca Ferretti(University of Oxford), Daniel Montero(IBM (United Kingdom)), James Warren(IBM (United Kingdom)), Nicole Mather(IBM (United Kingdom)), Matthew Abueg(Google (United States)), Neo Wu(Google (United States)), Olivier Legat(Google (United States)), Katie Bentley(King's College London), Thomas Mead(King's College London), Kelvin Van-Vuuren(The Francis Crick Institute), Dylan Feldner-Busztin(The Francis Crick Institute), Tommaso Ristori(Boston University), Anthony Finkelstein(The Alan Turing Institute), David Bonsall(University of Oxford), Lucie Abeler‐Dörner(University of Oxford), Christophe Fraser(Centre for Human Genetics)
PLoS Computational Biology
July 12, 2021
Cited by 213Open Access
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Abstract

SARS-CoV-2 has spread across the world, causing high mortality and unprecedented restrictions on social and economic activity. Policymakers are assessing how best to navigate through the ongoing epidemic, with computational models being used to predict the spread of infection and assess the impact of public health measures. Here, we present OpenABM-Covid19: an agent-based simulation of the epidemic including detailed age-stratification and realistic social networks. By default the model is parameterised to UK demographics and calibrated to the UK epidemic, however, it can easily be re-parameterised for other countries. OpenABM-Covid19 can evaluate non-pharmaceutical interventions, including both manual and digital contact tracing, and vaccination programmes. It can simulate a population of 1 million people in seconds per day, allowing parameter sweeps and formal statistical model-based inference. The code is open-source and has been developed by teams both inside and outside academia, with an emphasis on formal testing, documentation, modularity and transparency. A key feature of OpenABM-Covid19 are its Python and R interfaces, which has allowed scientists and policymakers to simulate dynamic packages of interventions and help compare options to suppress the COVID-19 epidemic.


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