A innovative prognostic symbol based on neutrophil extracellular traps (NETs)-related lncRNA signature in non-small-cell lung cancer

Fang Chen(Nanchang University), Fen Liu(First Affiliated Hospital of Nanchang University), Yong Wang(Nanchang University), Shangkun Yuan(Nanchang University), Renfang Chen(First Affiliated Hospital of Nanchang University), Xiaotong Qiu(First Affiliated Hospital of Nanchang University), Xiaoying Qian(First Affiliated Hospital of Nanchang University), Xinwei Zhang(First Affiliated Hospital of Nanchang University), Zhehao Xiao(First Affiliated Hospital of Nanchang University), Qian Wang(First Affiliated Hospital of Nanchang University), Biqi Fu(First Affiliated Hospital of Nanchang University), Yong Li(Nanchang University)
Aging
July 13, 2021
Cited by 38Open Access
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Abstract

< 0.001). Additionally, by RT-qPCR, we confirmed that NSCLC cell lines have higher levels of the three adverse prognostic NETs-related lncRNAs than normal lung cells. The expression of lncRNAs significantly increases after NETs stimulation. In short, the 12 NETs-related lncRNAs and their model could play effective roles as molecular markers in predicting survival for NSCLC patients.


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