NCCN Guidelines® Insights: Breast Cancer, Version 4.2021

William J. Gradishar(Robert H. Lurie Comprehensive Cancer Center of Northwestern University), Meena S. Moran(Smilow Cancer Hospital), Jame Abraham(Cleveland Clinic), Rebecca Aft(Barnes-Jewish Hospital), Doreen M. Agnese(The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute), Kimberly H. Allison(Cancer Institute (WIA)), Sarah L. Blair(University of California San Diego), Harold J. Burstein(Dana-Farber Brigham Cancer Center), Chau T. Dang(Memorial Sloan Kettering Cancer Center), Anthony Elias(University of Colorado Cancer Center), Sharon H. Giordano(The University of Texas MD Anderson Cancer Center), Matthew P. Goetz(Cancer Clinic), Lori J. Goldstein(Fox Chase Cancer Center), Sara A. Hurvitz(University of Colorado Cancer Center), Steven J. Isakoff(Massachusetts General Hospital), Rachel C. Jankowitz(University of Pennsylvania), Sara H. Javid(Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa), Jairam Krishnamurthy(Susan Thompson Buffett Foundation), Marilyn Leitch(Southwestern Medical Center), Janice A. Lyons(Cleveland Clinic), Jennifer M. Matro(University of Pennsylvania), Ingrid A. Mayer(Breast Cancer Research Foundation), Joanne Mortimer(City Of Hope National Medical Center), Ruth O’Regan(University of Wisconsin Carbone Cancer Center), Sameer A. Patel(Fox Chase Cancer Center), Lori J. Pierce(University of Michigan), Hope S. Rugo(UCSF Helen Diller Family Comprehensive Cancer Center), Amy M. Sitapati(University of California San Diego), Karen L. Smith(Sidney Kimmel Comprehensive Cancer Center), Mary Lou Smith(Research Advocacy Network), Hatem Soliman(Moffitt Cancer Center), Erica Stringer-Reasor(University of Colorado Cancer Center), Melinda L. Telli(Cancer Institute (WIA)), John H. Ward(University of Utah), Kari B. Wisinski(University of Wisconsin Carbone Cancer Center), Jessica Young, Jennifer L. Burns(National Comprehensive Cancer Network), Rashmi Kumar(National Comprehensive Cancer Network)
Journal of the National Comprehensive Cancer Network
May 1, 2021
10.6004/jnccn.2021.0023
Cited by 351Open Access
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Abstract

The NCCN Guidelines for Breast Cancer include up-to-date guidelines for clinical management of patients with carcinoma in situ, invasive breast cancer, Paget disease, phyllodes tumor, inflammatory breast cancer, male breast cancer, and breast cancer during pregnancy. These guidelines are developed by a multidisciplinary panel of representatives from NCCN Member Institutions with breast cancer-focused expertise in the fields of medical oncology, surgical oncology, radiation oncology, pathology, reconstructive surgery, and patient advocacy. These NCCN Guidelines Insights focus on the most recent updates to recommendations for adjuvant systemic therapy in patients with nonmetastatic, early-stage, hormone receptor-positive, HER2-negative breast cancer.

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