Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses

Sham Nambulli(University of Pittsburgh), Yufei Xiang(University of Pittsburgh), Natasha L. Tilston‐Lunel(University of Pittsburgh), Linda J. Rennick(University of Pittsburgh), Zhe Sang(University of Pittsburgh), William B. Klimstra(University of Pittsburgh), Douglas S. Reed(University of Pittsburgh), Nicholas A. Crossland(Boston University), Yi Shi(University of Pittsburgh), W. Paul Duprex(University of Pittsburgh)
Science Advances
May 26, 2021
10.1126/sciadv.abh0319
Cited by 167Open Access
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Abstract

Aerosol delivery of an ultrapotent nanobody efficiently prevents and treats SARS-CoV-2 infection.

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