DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

Chao Mao; Xiaoguang Liu; Yilei Zhang; Guang Lei; Yuelong Yan; Hyemin Lee; Pranavi Koppula; Shiqi Wu; Li Zhuang; Bingliang Fang; Masha V. Poyurovsky; Kellen Olszewski; Boyi Gan

doi:10.1038/s41586-021-03539-7

DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

Chao Mao(The University of Texas MD Anderson Cancer Center), Xiaoguang Liu(The University of Texas MD Anderson Cancer Center), Yilei Zhang(The University of Texas MD Anderson Cancer Center), Guang Lei(The University of Texas MD Anderson Cancer Center), Yuelong Yan(The University of Texas MD Anderson Cancer Center), Hyemin Lee(The University of Texas MD Anderson Cancer Center), Pranavi Koppula(The University of Texas MD Anderson Cancer Center), Shiqi Wu(The University of Texas MD Anderson Cancer Center), Li Zhuang(The University of Texas MD Anderson Cancer Center), Bingliang Fang(The University of Texas MD Anderson Cancer Center), Masha V. Poyurovsky(Eon Corporation (United States)), Kellen Olszewski(Eon Corporation (United States)), Boyi Gan(The University of Texas MD Anderson Cancer Center)

Nature

May 12, 2021

10.1038/s41586-021-03539-7

Cited by 1,760Open Access

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