Circulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients
Alana F. Ogata(Brigham and Women's Hospital), Chi‐An Cheng(Brigham and Women's Hospital), Michaël Desjardins(Brigham and Women's Hospital), Yasmeen Senussi(Brigham and Women's Hospital), Amy C Sherman(Brigham and Women's Hospital), Megan Powell(Brigham and Women's Hospital), Lewis A. Novack(Brigham and Women's Hospital), Salena S Von(Brigham and Women's Hospital), Xiaofang Li(Brigham and Women's Hospital), Lindsey R. Baden(Brigham and Women's Hospital), David R. Walt(Brigham and Women's Hospital)
Cited by 233Open Access
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins were measured in longitudinal plasma samples collected from 13 participants who received two doses of mRNA-1273 vaccine. Eleven of 13 participants showed detectable levels of SARS-CoV-2 protein as early as day 1 after first vaccine injection. Clearance of detectable SARS-CoV-2 protein correlated with production of immunoglobulin G (IgG) and immunoglobulin A (IgA).
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