FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathway

Zuhong He; Ming Li; Qiaojun Fang; Fu-ling Liao; Shengyu Zou; Xia Wu; Haiying Sun; Xueyan Zhao; Yujuan Hu; Xiaoxiang Xu; Sen Chen; Yu Sun; Renjie Chai; Weijia Kong

doi:10.1080/15548627.2021.1916194

FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathway

Zuhong He(Union Hospital), Ming Li(Union Hospital), Qiaojun Fang(State Key Laboratory of Digital Medical Engineering), Fu-ling Liao(Union Hospital), Shengyu Zou(Union Hospital), Xia Wu(Union Hospital), Haiying Sun(Union Hospital), Xueyan Zhao(Union Hospital), Yujuan Hu(Union Hospital), Xiaoxiang Xu(Hubei University of Arts and Science), Sen Chen(Union Hospital), Yu Sun(Union Hospital), Renjie Chai(Capital Medical University), Weijia Kong(Union Hospital)

Autophagy

May 19, 2021

10.1080/15548627.2021.1916194

Cited by 132Open Access

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Abstract

: AHL: age-related hearing loss; baf: bafilomycin A1; CD: common deletion; D-gal: D-galactose; GO: glucose oxidase; HC: hair cells; mtDNA: mitochondrial DNA; RAP: rapamycin; ROS: reactive oxygen species; TMRE: tetramethylrhodamine, ethyl ester.

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