CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity

Thi H. O. Nguyen; Louise C. Rowntree; Jan Petersen; Brendon Y. Chua; Luca Hensen; Łukasz Kedzierski; Carolien E. van de Sandt; Priyanka Chaurasia; Hyon‐Xhi Tan; Jennifer R. Habel; Wuji Zhang; Lilith F. Allen; Linda Earnest; Kai Yan Mak; Jennifer A. Juno; Kathleen M. Wragg; Francesca L. Mordant; Fatima Amanat; Florian Krammer; Nicole A. Mifsud; Denise L. Doolan; Katie L. Flanagan; Sabrina Sonda; Jasveen Kaur; Linda M. Wakim; Glen Westall; Fiona James; Effie Mouhtouris; Claire L. Gordon; Natasha E. Holmes; Olivia Smibert; Jason A. Trubiano; Allen Cheng; Peter Harcourt; Patrick Clifton; Jeremy Chase Crawford; Paul G. Thomas; Adam K. Wheatley; Stephen J. Kent; Jamie Rossjohn; Joseph Torresi; Katherine Kedzierska

doi:10.1016/j.immuni.2021.04.009

CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity

Thi H. O. Nguyen(The University of Melbourne), Louise C. Rowntree(The University of Melbourne), Jan Petersen(Australian Research Council), Brendon Y. Chua(The University of Melbourne), Luca Hensen(The University of Melbourne), Łukasz Kedzierski(The University of Melbourne), Carolien E. van de Sandt(The University of Melbourne), Priyanka Chaurasia(Australian Regenerative Medicine Institute), Hyon‐Xhi Tan(The University of Melbourne), Jennifer R. Habel(The University of Melbourne), Wuji Zhang(The University of Melbourne), Lilith F. Allen(The University of Melbourne), Linda Earnest(The University of Melbourne), Kai Yan Mak(The University of Melbourne), Jennifer A. Juno(The University of Melbourne), Kathleen M. Wragg(The University of Melbourne), Francesca L. Mordant(The University of Melbourne), Fatima Amanat(Icahn School of Medicine at Mount Sinai), Florian Krammer(Icahn School of Medicine at Mount Sinai), Nicole A. Mifsud(Australian Regenerative Medicine Institute), Denise L. Doolan(Australian Institute of Tropical Health and Medicine), Katie L. Flanagan(University of Tasmania), Sabrina Sonda(University of Tasmania), Jasveen Kaur(University of Tasmania), Linda M. Wakim(The University of Melbourne), Glen Westall(The Alfred Hospital), Fiona James(Austin Hospital), Effie Mouhtouris(Austin Hospital), Claire L. Gordon(The University of Melbourne), Natasha E. Holmes(The University of Melbourne), Olivia Smibert(Austin Hospital), Jason A. Trubiano(The University of Melbourne), Allen Cheng(Alfred Health), Peter Harcourt(Australian Football League), Patrick Clifton(Australian Football League), Jeremy Chase Crawford(St. Jude Children's Research Hospital), Paul G. Thomas(St. Jude Children's Research Hospital), Adam K. Wheatley(The University of Melbourne), Stephen J. Kent(The University of Melbourne), Jamie Rossjohn(Australian Research Council), Joseph Torresi(The University of Melbourne), Katherine Kedzierska(The University of Melbourne)

Immunity

April 16, 2021

10.1016/j.immuni.2021.04.009

Cited by 145Open Access

Full Text

Abstract

Related Papers

No related papers found

Powered by citation graph analysis