Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity
Takahiro Yoshizawa(Toho University), Ryohei Katayama(Japanese Foundation For Cancer Research)
Cited by 27
Related Papers
Brigatinib combined with anti-EGFR antibody overcomes osimertinib resistance in EGFR-mutated non-small-cell lung cancer
|Nature Communications|2017|409
P-glycoprotein Mediates Ceritinib Resistance in Anaplastic Lymphoma Kinase-rearranged Non-small Cell Lung Cancer
|EBioMedicine|2015|140
Prediction of ALK mutations mediating ALK-TKIs resistance and drug re-purposing to overcome the resistance
|EBioMedicine|2019|125
Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer
|Nature Communications|2021|100