A towering genome: Experimentally validated adaptations to high blood pressure and extreme stature in the giraffe
Chang Liu(Northwestern Polytechnical University), Jianbo Gao(Xijing Hospital), Xinxin Cui(Northwestern Polytechnical University), Zhipeng Li(Northwestern Polytechnical University), Lei Chen(Northwestern Polytechnical University), Yuan Yuan(Northwestern Polytechnical University), Yaolei Zhang, Liangwei Mei(Xijing Hospital), Lan Zhao(Northwest University), Dan Cai, Mingliang Hu(Northwestern Polytechnical University), Botong Zhou(Northwestern Polytechnical University), Zihe Li(Northwestern Polytechnical University), Tao Qin(Northwestern Polytechnical University), Huazhe Si(Jilin Agricultural University), Guangyu Li(Jilin Agricultural University), Zeshan Lin(Northwestern Polytechnical University), Yicheng Xu(Jiaxing University), Chenglong Zhu(Northwestern Polytechnical University), Yuan Yin(Northwestern Polytechnical University), Chenzhou Zhang(Northwestern Polytechnical University), Wenjie Xu(Northwestern Polytechnical University), Qingjie Li(The Affiliated Hospital to Changchun University of Chinese Medicine), Kun Wang(Northwestern Polytechnical University), M. Thomas P. Gilbert(University of Copenhagen), Rasmus Heller(University of Copenhagen), Wen Wang(Northwestern Polytechnical University), Jinghui Huang(Xijing Hospital), Qiang Qiu(Northwestern Polytechnical University)
Cited by 84Open Access
Abstract
show exceptional hypertension resistance and higher bone mineral density, both of which are tightly connected with giraffe adaptations to high stature. Our results facilitate a deeper understanding of the molecular mechanism underpinning distinct giraffe traits, and may provide insights into the study of hypertension in humans.
Related Papers
No related papers found
Powered by citation graph analysis