miR-375 prevents high-fat diet-induced insulin resistance and obesity by targeting the aryl hydrocarbon receptor and bacterial tryptophanase (<i>tnaA</i>) gene
Anil Kumar, Yi Ren(Nanjing Medical University), Kumaran Sundaram, Jingyao Mu, Mukesh K. Sriwastva, Gerald W. Dryden(University of Louisville), Chao Lei, Lifeng Zhang, Jun Yan, Xiang Zhang(University of Louisville), Juw Won Park(University of Louisville), Michael L. Merchant(University of Louisville), Yun Teng, Huang‐Ge Zhang(Louisville VA Medical Center)
Cited by 72Open Access
Abstract
Collectively our findings reveal that oral administration of GDNP to HFD mice improves host glucose tolerance and insulin response via regulating AhR expression by GDNP induced miR-375 and VAMP7.
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