Nicotinamide for the treatment of heart failure with preserved ejection fraction

Mahmoud Abdellatif; Viktoria Trummer-Herbst; Franziska Koser; Sylvère Durand; Rui Adão; Francisco Vasques‐Nóvoa; Johanna K. Freundt; Julia Voglhuber; María Rosaria Pricolo; Michael Kasa; Clara Türk; Fanny Aprahamian; Elías Herrero‐Galán; Sebastian J. Hofer; Tobias Pendl; Lavinia Rech; Julia Kargl; Nathaly Anto-Michel; Senka Ljubojević-Holzer; Julia Schipke; Christina Brandenberger; Martina Auer; Renate Schreiber; Chintan N. Koyani; Ákos Heinemann; Andreas Zirlik; Albrecht Schmidt; Dirk von Lewinski; Daniel Scherr; Peter P. Rainer; Julia von Maltzahn; Christian Mühlfeld; Marcus Krüger; Saša Frank; Frank Madeo; Tobias Eisenberg; Andreas Prokesch; Adelino Leite‐Moreira; André P. Lourenço; Jorge Alegre‐Cebollada; Stefan Kiechl; Wolfgang A. Linke; Guido Kroemer; Simon Sedej

doi:10.1126/scitranslmed.abd7064

Nicotinamide for the treatment of heart failure with preserved ejection fraction

Mahmoud Abdellatif(Medical University of Graz), Viktoria Trummer-Herbst(Medical University of Graz), Franziska Koser(University of Münster), Sylvère Durand(Inserm), Rui Adão(Universidade do Porto), Francisco Vasques‐Nóvoa(Universidade do Porto), Johanna K. Freundt(University of Münster), Julia Voglhuber(Medical University of Graz), María Rosaria Pricolo(Spanish National Centre for Cardiovascular Research), Michael Kasa(Medical University of Graz), Clara Türk(University of Cologne), Fanny Aprahamian(Inserm), Elías Herrero‐Galán(Spanish National Centre for Cardiovascular Research), Sebastian J. Hofer(Nawi Graz), Tobias Pendl(Nawi Graz), Lavinia Rech(Medical University of Graz), Julia Kargl(Medical University of Graz), Nathaly Anto-Michel(Medical University of Graz), Senka Ljubojević-Holzer(Medical University of Graz), Julia Schipke(Medizinische Hochschule Hannover), Christina Brandenberger(Medizinische Hochschule Hannover), Martina Auer(Medical University of Graz), Renate Schreiber(Nawi Graz), Chintan N. Koyani(Medical University of Graz), Ákos Heinemann(Medical University of Graz), Andreas Zirlik(Medical University of Graz), Albrecht Schmidt(Medical University of Graz), Dirk von Lewinski(Medical University of Graz), Daniel Scherr(Medical University of Graz), Peter P. Rainer(Medical University of Graz), Julia von Maltzahn(Leibniz Association), Christian Mühlfeld(Medizinische Hochschule Hannover), Marcus Krüger(University of Cologne), Saša Frank(Medical University of Graz), Frank Madeo(Nawi Graz), Tobias Eisenberg(Nawi Graz), Andreas Prokesch(Medical University of Graz), Adelino Leite‐Moreira(Universidade do Porto), André P. Lourenço(Universidade do Porto), Jorge Alegre‐Cebollada(Spanish National Centre for Cardiovascular Research), Stefan Kiechl(Innsbruck Medical University), Wolfgang A. Linke(University of Münster), Guido Kroemer(Karolinska University Hospital), Simon Sedej(Medical University of Graz)

Science Translational Medicine

February 10, 2021

10.1126/scitranslmed.abd7064

Cited by 207Open Access

Full Text

Abstract

precursors, and especially nicotinamide, as potential therapeutic agents to treat diastolic dysfunction and HFpEF in humans.

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