Risk factors prediction, clinical outcomes, and mortality in COVID‐19 patients

Roohallah Alizadehsani(Deakin University), Zahra Alizadeh Sani(Iran University of Medical Sciences), Mohaddeseh Behjati(Iran University of Medical Sciences), Zahra Roshanzamir(Children's Medical Center), Sadiq Hussain(Dibrugarh University), Niloofar Abedini(University of Tehran), Fereshteh Hasanzadeh(Omid Fertility Clinic), Abbas Khosravi(Deakin University), Afshin Shoeibi(K.N.Toosi University of Technology), Mohamad Roshanzamir(Islamic Azad University, Fasa Branch), Pardis Moradnejad(Iran University of Medical Sciences), Saeid Nahavandi(Deakin University), Fahime Khozeimeh(Deakin University), Assef Zare(Islamic Azad University, Tehran), Maryam Panahiazar(University of California, San Francisco), U. Rajendra Acharya(Asia University), Sheikh Mohammed Shariful Islam(Deakin University)
Journal of Medical Virology
November 28, 2020
Cited by 160Open Access
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Abstract

Preventing communicable diseases requires understanding the spread, epidemiology, clinical features, progression, and prognosis of the disease. Early identification of risk factors and clinical outcomes might help in identifying critically ill patients, providing appropriate treatment, and preventing mortality. We conducted a prospective study in patients with flu-like symptoms referred to the imaging department of a tertiary hospital in Iran between March 3, 2020, and April 8, 2020. Patients with COVID-19 were followed up after two months to check their health condition. The categorical data between groups were analyzed by Fisher's exact test and continuous data by Wilcoxon rank-sum test. Three hundred and nineteen patients (mean age 45.48 ± 18.50 years, 177 women) were enrolled. Fever, dyspnea, weakness, shivering, C-reactive protein, fatigue, dry cough, anorexia, anosmia, ageusia, dizziness, sweating, and age were the most important symptoms of COVID-19 infection. Traveling in the past 3 months, asthma, taking corticosteroids, liver disease, rheumatological disease, cough with sputum, eczema, conjunctivitis, tobacco use, and chest pain did not show any relationship with COVID-19. To the best of our knowledge, a number of factors associated with mortality due to COVID-19 have been investigated for the first time in this study. Our results might be helpful in early prediction and risk reduction of mortality in patients infected with COVID-19.


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