Dynamic not isometric training blunts osteo-renal disease and improves the sclerostin/FGF23/Klotho axis in maintenance hemodialysis patients: a randomized clinical trial
Rodrigo Vanerson Passos Neves(Universidade Católica de Brasília), Hugo de Luca Corrêa(Universidade Católica de Brasília), Lysleine Alves Deus(Universidade Católica de Brasília), Andrea Lucena Reis(Universidade Católica de Brasília), Michel Kendy Souza(Universidade Federal de São Paulo), Herbert Gustavo Simões(Universidade Católica de Brasília), James W. Navalta(University of Nevada, Las Vegas), Milton Rocha Moraes(Universidade Católica de Brasília), Jonato Prestes(Universidade Católica de Brasília), Thiago dos Santos Rosa(Universidade Católica de Brasília)
Cited by 40
Abstract
This study shows, for the first time, the effect of dynamic and isometric resistance training on bone mineral density in hemodialysis patients, providing a new understanding of the possible participation of the sclerostin/FGF23/Klotho axis, vitD, PTH, and calcium × phosphate product in this process. However, isometric resistance training may not be sufficient to induce these benefits. Therefore, this study supports the potential therapeutic role of dynamic resistance training counteracting chronic kidney disease-mineral and bone disorder.
Related Papers
No related papers found
Powered by citation graph analysis