A reference map of potential determinants for the human serum metabolome

Noam Bar; Tal Korem; Omer Weissbrod; David Zeevi; Daphna Rothschild; Sigal Leviatan; Noa Kosower; Maya Lotan‐Pompan; Adina Weinberger; Caroline Le Roy; Cristina Menni; Alessia Visconti; Mario Falchi; Tim D. Spector; Henrik Vestergaard; Manimozhiyan Arumugam; Torben Hansen; Kristine H. Allin; Tue H. Hansen; Mun‐Gwan Hong; Jochen M. Schwenk; Ragna S. Häussler; Matilda Dale; Toni Giorgino; Marianne Rodriquez; Mandy H. Perry; Rachel Nice; Timothy J. McDonald; Andrew T. Hattersley; Angus G. Jones; Ulrike Graefe‐Mody; Patrick Baum; Rolf Grempler; Cecilia Engel Thomas; Federico De Masi; Caroline Brorsson; Gianluca Mazzoni; Rosa Lundbye Allesøe; Simon Rasmussen; Valborg Guðmundsdóttir; Agnes Martine Nielsen; Karina Banasik; Konstantinos D. Tsirigos; Birgitte Nilsson; Helle Pedersen; Søren Brunak; Tugce Karaderi; Agnete Troen Lundgaard; Joachim Johansen; Ramneek Gupta; Peter Wad Sackett; J. Tillner; Thorsten Lehr; Nina Scherer; Christiane Dings; Iryna Sihinevich; Heather Loftus; Louise Cabrelli; Donna McEvoy; Andrea Mari; Roberto Bizzotto; Andrea Tura; Leen M. ‘t Hart; Koen F. Dekkers; Nienke van Leeuwen; Roderick C. Slieker; Femke Rutters; Joline W. J. Beulens; Giel Nijpels; Anitra D.M. Koopman; Sabine van Oort; Lenka Groeneveld; Leif Groop; Petra J. M. Elders; Ana Viñuela; Anna Ramisch; Emmanouil Dermitzakis; Beate Ehrhardt; Christopher Jennison; Philippe Froguel; Mickaël Canouil; Amélie Boneford; Ian McVittie; Dianne Wake; Francesca Frau; Hans‐Henrik Stærfeldt; Kofi P. Adragni; Melissa K. Thomas; Han Wu; Imre Pavo; Birgit Steckel-Hamann; Henrik S. Thomsen; Giuseppe N. Giordano; Hugo Fitipaldi; Martin Ridderstråle; Azra Kurbasic; Naeimeh Atabaki Pasdar; Hugo Pomares‐Millan; Pascal M. Mutie; Robert W. Koivula; Nicky McRobert; Mark I. McCarthy; Agata Wesolowska‐Andersen; Anubha Mahajan; Moustafa Abdalla; Juan Fernandez; Reinhard W. Holl; Alison Heggie; Harshal Deshmukh; Anita M. Hennige; Susanna Bianzano; Barbara Thorand; Sapna Sharma; Harald Grallert; Jonathan Adam; Martina Troll; Andreas Fritsche; Anita Hill; Claire E. Thorne; Michelle Hudson; Teemu Kuulasmaa; Jagadish Vangipurapu; Markku Laakso; Henna Cederberg; Tarja Kokkola; Yunlong Jiao; Stephen Gough; Neil Robertson; Hélène Verkindt; Violeta Raverdi; Robert Caïazzo; François Pattou; Margaret H. White; Louise A. Donnelly; Andrew Brown; Colin Palmer; David Davtian; Adem Y. Dawed; Ian Forgie; Ewan R. Pearson; Hartmut Ruetten; Petra Musholt; Jimmy D. Bell; E. Louise Thomas; Brandon Whitcher; Mark Haid; Claudia Nicolay; Miranda Mourby; Jane Kaye; Nisha Shah; Harriet Teare; Gary Frost; Bernd Jablonka; Mathias Uhlén; Rebeca Eriksen; Josef Korbinian Vogt; Avirup Dutta; Anna Jönsson; Line Engelbrechtsen; Annemette Forman; Nadja B. Søndertoft; Nathalie de Préville; Tania Baltauss; Mark Walker; Johann Gassenhuber; Maria Klintenberg; Margit Bergstrom; Jorge Ferrer; Jerzy Adamski; Paul W. Franks; Oluf Pedersen; Eran Segal

doi:10.1038/s41586-020-2896-2

A reference map of potential determinants for the human serum metabolome

Noam Bar(Weizmann Institute of Science), Tal Korem(Canadian Institute for Advanced Research), Omer Weissbrod(Harvard University), David Zeevi(Weizmann Institute of Science), Daphna Rothschild(Weizmann Institute of Science), Sigal Leviatan(Weizmann Institute of Science), Noa Kosower(Weizmann Institute of Science), Maya Lotan‐Pompan(Weizmann Institute of Science), Adina Weinberger(Weizmann Institute of Science), Caroline Le Roy(King's College London), Cristina Menni(King's College London), Alessia Visconti(King's College London), Mario Falchi(King's College London), Tim D. Spector(King's College London), Henrik Vestergaard(University of Copenhagen), Manimozhiyan Arumugam(University of Copenhagen), Torben Hansen(University of Copenhagen), Kristine H. Allin(University of Copenhagen), Tue H. Hansen(University of Copenhagen), Mun‐Gwan Hong(Science for Life Laboratory), Jochen M. Schwenk(Science for Life Laboratory), Ragna S. Häussler(Science for Life Laboratory), Matilda Dale(Science for Life Laboratory), Toni Giorgino(University of Milan), Marianne Rodriquez, Mandy H. Perry(Royal Devon & Exeter NHS Foundation Trust), Rachel Nice(Royal Devon & Exeter NHS Foundation Trust), Timothy J. McDonald(University of Exeter), Andrew T. Hattersley(University of Exeter), Angus G. Jones(University of Exeter), Ulrike Graefe‐Mody(Boehringer Ingelheim (Germany)), Patrick Baum(Boehringer Ingelheim (Germany)), Rolf Grempler(Boehringer Ingelheim (Germany)), Cecilia Engel Thomas(University of Copenhagen), Federico De Masi(University of Copenhagen), Caroline Brorsson(University of Copenhagen), Gianluca Mazzoni(University of Copenhagen), Rosa Lundbye Allesøe(University of Copenhagen), Simon Rasmussen(University of Copenhagen), Valborg Guðmundsdóttir(University of Copenhagen), Agnes Martine Nielsen(University of Copenhagen), Karina Banasik(University of Copenhagen), Konstantinos D. Tsirigos(University of Copenhagen), Birgitte Nilsson(University of Copenhagen), Helle Pedersen(University of Copenhagen), Søren Brunak(University of Copenhagen), Tugce Karaderi(University of Copenhagen), Agnete Troen Lundgaard(University of Copenhagen), Joachim Johansen(University of Copenhagen), Ramneek Gupta(Technical University of Denmark), Peter Wad Sackett(Technical University of Denmark), J. Tillner(Sanofi (Germany)), Thorsten Lehr(Saarland University), Nina Scherer(Saarland University), Christiane Dings(Saarland University), Iryna Sihinevich(Saarland University), Heather Loftus(University of Dundee), Louise Cabrelli(University of Dundee), Donna McEvoy(Royal Victoria Infirmary), Andrea Mari(Neuroscience Institute), Roberto Bizzotto(Neuroscience Institute), Andrea Tura(Neuroscience Institute), Leen M. ‘t Hart(Leiden University Medical Center), Koen F. Dekkers(Leiden University Medical Center), Nienke van Leeuwen(Leiden University Medical Center), Roderick C. Slieker(Leiden University Medical Center), Femke Rutters(Amsterdam Public Health), Joline W. J. Beulens(Amsterdam Public Health), Giel Nijpels(Amsterdam Public Health), Anitra D.M. Koopman(Amsterdam Public Health), Sabine van Oort(Amsterdam Public Health), Lenka Groeneveld(Amsterdam Public Health), Leif Groop(Lund University), Petra J. M. Elders(Amsterdam University Medical Centers), Ana Viñuela(University of Geneva), Anna Ramisch(University of Geneva), Emmanouil Dermitzakis(University of Geneva), Beate Ehrhardt(University of Bath), Christopher Jennison(University of Bath), Philippe Froguel(Centre National de la Recherche Scientifique), Mickaël Canouil(Centre National de la Recherche Scientifique), Amélie Boneford(Centre National de la Recherche Scientifique), Ian McVittie(Royal Victoria Infirmary), Dianne Wake(Royal Victoria Infirmary), Francesca Frau(Sanofi (Germany)), Hans‐Henrik Stærfeldt(Technical University of Denmark), Kofi P. Adragni(Eli Lilly (United States)), Melissa K. Thomas(Eli Lilly (United States)), Han Wu(Eli Lilly (United States)), Imre Pavo, Birgit Steckel-Hamann, Henrik S. Thomsen(University of Copenhagen), Giuseppe N. Giordano(Lund University), Hugo Fitipaldi(Lund University), Martin Ridderstråle(Lund University), Azra Kurbasic(Lund University), Naeimeh Atabaki Pasdar(Lund University), Hugo Pomares‐Millan(Lund University), Pascal M. Mutie(Lund University), Robert W. Koivula(Lund University), Nicky McRobert(University of Oxford), Mark I. McCarthy(Centre for Human Genetics), Agata Wesolowska‐Andersen(University of Oxford), Anubha Mahajan(Centre for Human Genetics), Moustafa Abdalla(Centre for Human Genetics), Juan Fernandez(Centre for Human Genetics), Reinhard W. Holl(Universität Ulm), Alison Heggie(Newcastle University), Harshal Deshmukh(Newcastle University), Anita M. Hennige(Boehringer Ingelheim (Germany)), Susanna Bianzano(Boehringer Ingelheim (Germany)), Barbara Thorand(Helmholtz Zentrum München), Sapna Sharma(Helmholtz Zentrum München), Harald Grallert(Helmholtz Zentrum München), Jonathan Adam(Helmholtz Zentrum München), Martina Troll(Helmholtz Zentrum München), Andreas Fritsche(Universitätsklinikum Tübingen), Anita Hill(University of Exeter), Claire E. Thorne(University of Exeter), Michelle Hudson(University of Exeter), Teemu Kuulasmaa(University of Eastern Finland), Jagadish Vangipurapu(University of Eastern Finland), Markku Laakso(University of Eastern Finland), Henna Cederberg(University of Eastern Finland), Tarja Kokkola(University of Eastern Finland), Yunlong Jiao(University of Oxford), Stephen Gough(University of Oxford), Neil Robertson(University of Oxford), Hélène Verkindt(Inserm), Violeta Raverdi(Inserm), Robert Caïazzo(Inserm), François Pattou(Inserm), Margaret H. White(University of Dundee), Louise A. Donnelly(University of Dundee), Andrew Brown(University of Dundee), Colin Palmer(University of Dundee), David Davtian(University of Dundee), Adem Y. Dawed(University of Dundee), Ian Forgie(University of Dundee), Ewan R. Pearson(University of Dundee), Hartmut Ruetten(Boehringer Ingelheim (Germany)), Petra Musholt(Sanofi (Germany)), Jimmy D. Bell(University of Westminster), E. Louise Thomas(University of Westminster), Brandon Whitcher(University of Westminster), Mark Haid(Helmholtz Zentrum München), Claudia Nicolay(Eli Lilly (Germany)), Miranda Mourby(University of Oxford), Jane Kaye(University of Oxford), Nisha Shah(University of Oxford), Harriet Teare(University of Oxford), Gary Frost(Imperial College London), Bernd Jablonka(Sanofi (Germany)), Mathias Uhlén(Science for Life Laboratory), Rebeca Eriksen(Imperial College London), Josef Korbinian Vogt(University of Copenhagen), Avirup Dutta(University of Copenhagen), Anna Jönsson(University of Copenhagen), Line Engelbrechtsen(University of Copenhagen), Annemette Forman(University of Copenhagen), Nadja B. Søndertoft(University of Copenhagen), Nathalie de Préville(Servier (France)), Tania Baltauss(Servier (France)), Mark Walker(Newcastle University), Johann Gassenhuber(Sanofi (Germany)), Maria Klintenberg, Margit Bergstrom, Jorge Ferrer(Consorci Institut D'Investigacions Biomediques August Pi I Sunyer), Jerzy Adamski(National University of Singapore), Paul W. Franks(Harvard University), Oluf Pedersen(University of Copenhagen), Eran Segal(Weizmann Institute of Science)

Nature

November 11, 2020

10.1038/s41586-020-2896-2

Cited by 445Open Access

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