Inherited causes of clonal haematopoiesis in 97,691 whole genomes
Alexander G. Bick(Broad Institute), Joshua S. Weinstock(University of Michigan), Satish K. Nandakumar(Broad Institute), Charles P. Fulco(Broad Institute), Erik L. Bao(Broad Institute), Seyedeh M. Zekavat(Broad Institute), Mindy D Szeto(University of Colorado Anschutz Medical Campus), Xiaotian Liao(Broad Institute), Matthew Leventhal(Broad Institute), Joseph Nasser(Broad Institute), Kyle Chang(The University of Texas MD Anderson Cancer Center), Cecelia Laurie(University of Washington), Bala Bharathi Burugula(University of Michigan), Christopher J. Gibson(Dana-Farber Cancer Institute), Abhishek Niroula(Broad Institute), Amy E. Lin(Brigham and Women's Hospital), Margaret A. Taub(Johns Hopkins University), François Aguet(Broad Institute), Kristin Ardlie(Broad Institute), Braxton D. Mitchell(University of Maryland, Baltimore), Kathleen C. Barnes(University of Colorado Anschutz Medical Campus), Arden Moscati(Icahn School of Medicine at Mount Sinai), Myriam Fornage(Brown Foundation), Susan Redline(Brigham and Women's Hospital), Bruce M. Psaty(Kaiser Permanente Washington Health Research Institute), Edwin K. Silverman(Brigham and Women's Hospital), Scott T. Weiss(Brigham and Women's Hospital), Nicholette D. Palmer(Wake Forest University), Ramachandran S. Vasan(Boston University), Esteban G. Burchard(University of California, San Francisco), Sharon L. R. Kardia(University of Michigan), Jiang He(Tulane University), Robert C. Kaplan(Albert Einstein College of Medicine), Nicholas L. Smith(Kaiser Permanente Washington Health Research Institute), Donna K. Arnett(University of Kentucky), David A. Schwartz(University of Colorado Anschutz Medical Campus), Adolfo Correa(University of Mississippi Medical Center), Mariza de Andrade(Mayo Clinic in Florida), Xiuqing Guo(The Lundquist Institute), Barbara A. Konkle(University of Washington), Brian Custer(University of California, San Francisco), Juan M. Peralta(The University of Texas Rio Grande Valley), Hongsheng Gui(Henry Ford Health System), Deborah A. Meyers(University of Arizona), Stephen T. McGarvey(Brown University), Ida Yii-Der Chen(The Lundquist Institute), M. Benjamin Shoemaker(Vanderbilt University Medical Center), Patricia A. Peyser(University of Michigan), Jai Broome(University of Washington), Stephanie M. Gogarten(University of Washington), Fei Fei Wang(University of Washington), Quenna Wong(University of Washington), May E. Montasser(University of Maryland, Baltimore), Michelle Daya(University of Colorado Anschutz Medical Campus), Eimear E. Kenny(Genomic Health (United States)), Kari E. North(University of North Carolina at Chapel Hill), Lenore J. Launer(National Institute on Aging), Brian E. Cade(Brigham and Women's Hospital), Joshua C. Bis(University of Washington), Michael H. Cho(Brigham and Women's Hospital), Jessica Lasky‐Su(Brigham and Women's Hospital), Donald W. Bowden(Wake Forest University), L. Adrienne Cupples(Boston University), Angel C. Y. Mak(University of California, San Francisco), Lewis C. Becker(Johns Hopkins University), Jennifer A. Smith(University of Michigan), Tanika N. Kelly(Tulane University), Stella Aslibekyan(University of Alabama at Birmingham), Susan R. Heckbert(Kaiser Permanente Washington Health Research Institute), Hemant K. Tiwari(University of Alabama at Birmingham), Ivana V. Yang(University of Colorado Anschutz Medical Campus), John A. Heit(Mayo Clinic in Arizona), Steven A. Lubitz(Broad Institute), Jill M. Johnsen(University of Washington), Joanne E. Curran(The University of Texas Rio Grande Valley), Sally E. Wenzel(University of Pittsburgh), Daniel E. Weeks(University of Pittsburgh), D. C. Rao(Washington University in St. Louis), Dawood Darbar(University of Illinois Chicago), Jee‐Young Moon(Albert Einstein College of Medicine), Russell P. Tracy(University of Vermont), Erin Buth(University of Washington), Nicholas Rafaels(University of Colorado Anschutz Medical Campus), Ruth J. F. Loos(Child Health and Development Institute), Peter Durda(University of Vermont), Yongmei Liu(Duke Medical Center), Lifang Hou(Northwestern University), Jiwon Lee(Brigham and Women's Hospital), Priyadarshini Kachroo(Brigham and Women's Hospital), Barry I. Freedman(Wake Forest University), Daniel Levy(National Institutes of Health), Lawrence F. Bielak(University of Michigan), James E. Hixson(The University of Texas Health Science Center at Houston), James S. Floyd(University of Washington), Eric A. Whitsel(University of North Carolina at Chapel Hill), Patrick T. Ellinor(Broad Institute), Marguerite R. Irvin(University of Alabama at Birmingham), Tasha E. Fingerlin(National Jewish Health), Laura M. Raffield(University of North Carolina at Chapel Hill), Sebastian M. Armasu(Mayo Clinic in Florida), Marsha M. Wheeler(University of Washington), Éster Cerdeira Sabino(Universidade de São Paulo), John Blangero(The University of Texas Rio Grande Valley), Lawrence K. Williams(Henry Ford Health System), Bruce D. Levy(Brigham and Women's Hospital), Wayne Huey‐Herng Sheu(Taichung Veterans General Hospital), Dan M. Roden(Vanderbilt University Medical Center), Eric Boerwinkle(Baylor College of Medicine), JoAnn E. Manson(Brigham and Women's Hospital), Rasika A. Mathias(Johns Hopkins University), Pinkal Desai(Cornell University), Kent D. Taylor(UCLA Medical Center), Andrew D. Johnson(National Institutes of Health), Namiko Abe(New York Genome Center), Christine M. Albert(Brigham and Women's Hospital), Laura Almasy(Children's Hospital of Philadelphia), Alvaro Alonso(Emory University), Seth A. Ament(University of Maryland, Baltimore), Peter Anderson(University of Washington), Pramod Anugu(University of Mississippi), Deborah Applebaum‐Bowden(National Institutes of Health), Dan Arking(Johns Hopkins University), Allison E. Ashley‐Koch(Duke University), Stella Aslibekyan(University of Alabama at Birmingham), Tim Assimes(Stanford University), Dimitrios Avramopoulos(Johns Hopkins University), John Barnard(Cleveland Clinic), R. Graham Barr(Columbia University), Emily Barron‐Casella(Johns Hopkins University), Lucas Barwick(Emmes (United States)), Terri Beaty(Johns Hopkins University), Gerald J. Beck(Cleveland Clinic), Diane M. Becker(Johns Hopkins University), Rebecca Beer(National Institutes of Health), Amber L. Beitelshees(University of Maryland, Baltimore), Emelia J. Benjamin(Boston University), P.V. Benos(University of Pittsburgh), Marcos Bezerra(Fundação Hemopa), Larry Bielak(University of Michigan), Russell P. Bowler(National Jewish Health), Jennifer A. Brody(University of Washington), Ulrich Broeckel(Medical College of Wisconsin), Karen Bunting(New York Genome Center), Carlos D. Bustamante(Stanford University), Jonathan Cardwell(University of Colorado Anschutz Medical Campus), Vincent J. Carey(Brigham and Women's Hospital), Cara L. Carty(Washington State University), Richard Casaburi(University of California, Los Angeles), James F. Casella(Johns Hopkins University), Peter J. Castaldi(Baylor College of Medicine), Mark Chaffin(Broad Institute), Christy Chang(University of Maryland, Baltimore), Yi‐Cheng Chang(National Taiwan University Hospital), Daniel I. Chasman(Brigham and Women's Hospital), Sameer Chavan(University of Colorado Anschutz Medical Campus), Bo-Juen Chen(New York Genome Center), Wei‐Min Chen(University of Virginia), Seung Hoan Choi(Broad Institute), Lee‐Ming Chuang(National Taiwan University Hospital), Mina K. Chung(Cleveland Clinic), Ren‐Hua Chung(National Health Research Institutes), Clary B. Clish(Broad Institute), Suzy Comhair(University of Washington), Elaine Cornell(University of Vermont), Carolyn Crandall(University of California, Los Angeles), James D. Crapo(National Jewish Health), Jeffrey L. Curtis(University of Michigan), Coleen Damcott(University of Maryland, Baltimore), Sayantan Das(University of Michigan), Sean P. David(University of Illinois Chicago), Colleen Davis(University of Washington), Michael R. DeBaun(Vanderbilt University), Ranjan Deka(University of Cincinnati), Dawn L. DeMeo(Washington University in St. Louis), Scott E. Devine(University of Maryland, Baltimore), Qing Duan(University of North Carolina at Chapel Hill), Ravi Duggirala(The University of Texas Rio Grande Valley), Susan K. Dutcher(Washington University in St. Louis), Charles B. Eaton(Brown University), Lynette Ekunwe(University of Mississippi), Adel Boueiz(Brigham and Women's Hospital), Leslie S. Emery(University of Washington), Serpil C. Erzurum(Cleveland Clinic), Charles R. Farber(University of Washington), Matthew Flickinger(University of Michigan), Nora Franceschini(University of North Carolina at Chapel Hill), Chris Frazar(University of Washington), Mao Fu(University of Maryland, Baltimore), Stephanie M. Fullerton(University of Washington), Lucinda A. Fulton(Washington University in St. Louis), Stacey Gabriel(University of Michigan), Weiniu Gan(National Institutes of Health), Shanshan Gao(University of Colorado Anschutz Medical Campus), Yan Gao(University of Mississippi), Margery Gass(Fred Hutch Cancer Center), Bruce D. Gelb(Icahn School of Medicine at Mount Sinai), Xiaoqi Geng, Mark W. Geraci(Indiana University – Purdue University Indianapolis), Søren Germer(New York Genome Center), Robert E. Gerszten(Harvard University), Auyon Ghosh(Baylor College of Medicine), Richard A. Gibbs(Baylor College of Medicine), Chris Gignoux(University of Colorado Anschutz Medical Campus), Mark T. Gladwin(University of Pittsburgh), David C. Glahn(Yale University), Da‐Wei Gong(University of Maryland, Baltimore), Harald H.H. Göring(The University of Texas Rio Grande Valley), Sharon Graw(University of Colorado Anschutz Medical Campus), Daniel Grine(University of Colorado Anschutz Medical Campus), C. Charles Gu(Washington University in St. Louis), Yue Guan(University of Maryland, Baltimore), Namrata Gupta(Harvard University), Jeff Haessler(University of Colorado Anschutz Medical Campus), Michael E. Hall(University of Mississippi), Daniel Harris(University of Maryland, Baltimore), Nicola L. Hawley(Yale University), Ben Heavner(University of Washington), Ryan D. Hernandez(McGill University), David Herrington(Atrium Health Wake Forest Baptist), Craig P. Hersh(Brigham and Women's Hospital), Bertha Hidalgo(University of Alabama at Birmingham), Brian D. Hobbs(Baylor College of Medicine), John E. Hokanson(University of Colorado Anschutz Medical Campus), Elliott Hong(University of Maryland, Baltimore), Karin F. Hoth(University of Iowa), Chao A. Hsiung, Yi‐Jen Hung(Tri-Service General Hospital), Haley Huston(Bloodworks Northwest), Chii Min Hwu(Taichung Veterans General Hospital), Rebecca D. Jackson(The Ohio State University Wexner Medical Center), Deepti Jain(University of Washington), Cashell E. Jaquish(National Institutes of Health), Min A. Jhun(University of Michigan), Craig Johnson(University of Washington), Rich Johnston(Emory University), Kimberly Jones(Johns Hopkins University), Hyun Min Kang(University of Washington), Shannon Kelly(Johns Hopkins University), Michael Kessler(University of Maryland, Baltimore), Alyna Khan(University of Washington), Wonji Kim(Brigham and Women's Hospital), Gregory L. Kinney(University of Colorado Anschutz Medical Campus), Holly Kramer(Loyola University Chicago), Christoph Lange(Harvard University), Meryl S. LeBoff(University of California, San Francisco), Seunggeun Shawn Lee(University of Michigan), Wen‐Jane Lee(Taichung Veterans General Hospital), Jonathon LeFaive(University of Michigan), David Levine(University of Washington), Joshua P. Lewis(University of Maryland, Baltimore), Xiaohui Li(Brown University), Yun Li(University of North Carolina at Chapel Hill), Henry J. Lin, Honghuang Lin, Keng Han Lin(University of Michigan), Xihong Lin(Harvard University), Simin Liu(Brown University), Yu Liu(Cardiovascular Institute of the South), Kathryn L. Lunetta, James Luo(National Institutes of Health), Michael C. Mahaney(The University of Texas Rio Grande Valley), Barry J. Make(Johns Hopkins University), Ani Manichaikul(University of Wisconsin–Milwaukee), Lauren Margolin(Broad Institute), Lisa Martin(Children's Hospital of Philadelphia), Susan Mathai(University of Colorado Anschutz Medical Campus), Susanne May(University of Washington), Patrick F. McArdle(University of Maryland, Baltimore), Merry‐Lynn McDonald(University of Alabama at Birmingham), Sean McFarland(Boston Children's Hospital), Daniel McGoldrick(University of Washington), Caitlin McHugh(University of Washington), Hao Mei(University of Mississippi), Luisa Mestroni(University of Colorado Anschutz Medical Campus), Julie Mikulla(National Institutes of Health), Yuan‐I Min(University of Mississippi), Mollie Minear(National Institutes of Health), Ryan L. Minster(University of Pittsburgh), Matt Moll(Brigham and Women's Hospital), Courtney G. Montgomery(Oklahoma Medical Research Foundation), Solomon K. Musani(University of Mississippi Medical Center), Stanford Mwasongwe(University of Mississippi), Josyf C. Mychaleckyj(University of Virginia), Girish N. Nadkarni(Icahn School of Medicine at Mount Sinai), Rakhi P. Naik(Johns Hopkins University), Take Naseri(National University of Samoa), Sergeï Nekhai(Howard University), Sarah C. Nelson(University of Washington), Bonnie Neltner(University of Colorado Anschutz Medical Campus), Deborah A. Nickerson(University of Washington), Jeff O’Connell(University of Maryland, Baltimore), Tim O’Connor(University of Maryland, Baltimore), Heather M. Ochs‐Balcom(University at Buffalo, State University of New York), David T. Paik(Cardiovascular Institute of the South), James S. Pankow(University of Minnesota), George Papanicolaou(National Institutes of Health), Afshin Parsa(University of Maryland, Baltimore), Marco Perez(Stanford University), James A. Perry(University of Maryland, Baltimore), Ulrike Peters(Fred Hutch Cancer Center), Patricia A. Peyser(University of Michigan), Lawrence S. Phillips(Emory University), Toni I. Pollin(University of Maryland, Baltimore), Wendy S. Post(Johns Hopkins University), Julia Powers Becker(University of Colorado Anschutz Medical Campus), Meher Preethi Boorgula(University of Colorado Anschutz Medical Campus), Michael Preuß(Icahn School of Medicine at Mount Sinai), Pankaj Qasba(National Institutes of Health), Dandi Qiao(Brigham and Women's Hospital), Zhaohui Qin(Emory University), Laura J. Rasmussen‐Torvik(Northwestern University), Aakrosh Ratan(University of Virginia), Robert D. Reed(University of Maryland, Baltimore), Elizabeth A. Regan(National Jewish Health), Muagututi‘a Sefuiva Reupena(University of Cincinnati), Kenneth Rice(University of Washington), Carolina Roselli(Broad Institute), Ingo Ruczinski(Johns Hopkins University), Pamela Russell(University of Colorado Anschutz Medical Campus), Sarah Ruuska(Bloodworks Northwest), Kathleen A. Ryan(University of Maryland, Baltimore), Danish Saleheen(Columbia University), Shabnam Salimi(University of Maryland, Baltimore), Steven L. Salzberg(Johns Hopkins University), Kevin Sandow, Christopher Scheller(University of Michigan), Ellen M. Schmidt(University of Michigan), Karen Schwander(Washington University in St. Louis), Frank C. Sciurba(University of Pittsburgh), Christine E. Seidman(Howard Hughes Medical Institute), Jonathan G. Seidman(Broad Institute), Vivien Sheehan(Baylor College of Medicine), Stephanie L. Sherman(Emory University), Amol C. Shetty(University of Maryland, Baltimore), Aniket Shetty(University of Colorado Anschutz Medical Campus), Brian Silver(UMass Memorial Health Care), Josh Smith(University of Washington), Tanja Smith(New York Genome Center), Sylvia Smoller(Albert Einstein College of Medicine), Beverly M. Snively(Atrium Health Wake Forest Baptist), M Snyder(Stanford University), Tamar Sofer(Harvard University), Nona Sotoodehnia(University of Washington), Adrienne M. Stilp(University of Washington), Garrett Storm(University of Colorado Anschutz Medical Campus), Elizabeth A. Streeten(University of Maryland, Baltimore), Jessica Lasky‐Su(Brigham and Women's Hospital), Yun Ju Sung(Washington University in St. Louis), Jody Sylvia(University of California, San Francisco), Adam A. Szpiro(University of Washington), Carole Sztalryd(University of Maryland, Baltimore), Daniel Taliun(University of Michigan), Hua Tang(Stanford University), Matthew R.G. Taylor(University of Colorado Anschutz Medical Campus), Simeon I. Taylor(University of Maryland, Baltimore), Marilyn J. Telen(Duke University), Timothy A. Thornton(University of Washington), Machiko Threlkeld(Oklahoma Medical Research Foundation), Lesley Tinker(University of Colorado Anschutz Medical Campus), David Tirschwell(University of Washington), Sarah A. Tishkoff(University of Pennsylvania), Hemant Tiwari(University of Alabama at Birmingham), Catherine Tong(University of Washington), Michael Tsai(University of Minnesota), Dhananjay Vaidya(Johns Hopkins University), David Van Den Berg(University of Southern California), Peter VandeHaar(University of Michigan), Scott Vrieze(University of Minnesota), Tarik Walker(University of Colorado Anschutz Medical Campus), Robert B. Wallace(Tri-Service General Hospital), Avram Walts(University of Colorado Anschutz Medical Campus), Heming Wang(Brigham and Women's Hospital), Karol Watson(University of California, Los Angeles), Bruce S. Weir(University of Washington), Lu‐Chen Weng(Massachusetts General Hospital), Jennifer Wessel(Indiana University – Purdue University Indianapolis), Cristen J. Willer(University of Michigan), Kayleen Williams(University of Washington), Carla G. Wilson(National Jewish Health), Joseph C. Wu(Cardiovascular Institute of the South), Huichun Xu(University of Maryland, Baltimore), Lisa R. Yanek(Johns Hopkins University), Rongze Yang(University of Maryland, Baltimore), Norann A. Zaghloul(University of Maryland, Baltimore), Yingze Zhang(University of Pittsburgh), Snow Xueyan Zhao(University of California, San Francisco), Wei Zhao(Broad Institute), Degui Zhi, Xiang Zhou(University of Michigan), Xiaofeng Zhu(Case Western Reserve University), Michael C. Zody(New York Genome Center), Sebastian Zoellner(University of Michigan), Paul L. Auer(University of Wisconsin–Milwaukee), Charles Kooperberg(Fred Hutch Cancer Center), Cathy C. Laurie(University of Washington), Thomas W. Blackwell(University of Michigan), Albert V. Smith(University of Michigan), Hongyu Zhao(Yale University), Ethan M. Lange(University of Colorado Anschutz Medical Campus), Leslie Lange(University of Colorado Anschutz Medical Campus), Stephen S. Rich(Office of Public Health Genomics), Jerome I. Rotter(UCLA Medical Center), James Wilson(Beth Israel Deaconess Medical Center), Paul Scheet(The University of Texas MD Anderson Cancer Center), Jacob O. Kitzman(University of Michigan), Eric S. Lander(Broad Institute), J Engreitz(Broad Institute), Benjamin L. Ebert(Broad Institute), Alex P. Reiner(University of Washington), Siddhartha Jaiswal(Stanford University), Gonçalo R. Abecasis(Regeneron (United States)), Vijay G. Sankaran(Broad Institute), Sekar Kathiresan(Broad Institute), Pradeep Natarajan(Broad Institute)
Cited by 734Open Access
Abstract
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