WUSCHEL triggers innate antiviral immunity in plant stem cells
Haijun Wu(University of Science and Technology of China), Xiaoya Qu(University of Science and Technology of China), Zhicheng Dong(Guangzhou University), Linjie Luo(University of Science and Technology of China), Chen Shao(University of Science and Technology of China), Joachim Forner(Heidelberg University), Jan U. Lohmann(Heidelberg University), Meng Su(University of Science and Technology of China), Mengchu Xu(University of Science and Technology of China), Xiaobin Liu(Guangzhou University), Lei Zhu(Sichuan University), Jian Zeng(University of Science and Technology of China), Sumei Liu(University of Science and Technology of China), Zhaoxia Tian(University of Science and Technology of China), Zhong Zhao(University of Science and Technology of China)
Cited by 144
Abstract
Building a safe space for stem cells The meristem, the collection of stem cells that builds plants, is resistant to viral infection. Wu et al. now show that WUSCHEL, a transcription factor that helps to sustain stem cell production in the shoot apical meristem of Arabidopsis , also protects that stem cell domain from viruses. WUSCHEL inhibited viral protein synthesis by repressing methyltransferases that regulate ribosomal RNA processing and ribosome stability. Science , this issue p. 227
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