Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson; Cristovão M. Sousa; Xiaoyu Zhang; Eiru Kim; Rummy Akthar; Joseph J. Caumanns; Yuxi Yao; Nicholas Mikolajewicz; Catherine Ross; Kevin R. Brown; Abdelrahman Abou Zid; Zi Peng Fan; Shirley Hui; Jordan A. Krall; Donald M. Simons; Chloe J. Slater; Víctor R. De Jesús; Lujia Tang; Richa Singh; Joshua E. Goldford; Sarah L. Fordyce Martin; Qian Huang; Elizabeth Francis; Andrea Habsid; Ryan Climie; David Tieu; Jiarun Wei; Li Ren; Amy H.Y. Tong; Michael Aregger; Katherine Chan; Hong Han; Xiaowei Wang; Patricia Mero; John H. Brumell; Antonio Finelli; Laurie Ailles; Gary D. Bader; Gromoslaw A. Smolen; Gillian A. Kingsbury; Traver Hart; Charles Kung; Jason Moffat

doi:10.1038/s41586-020-2746-2

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson(University Health Network), Cristovão M. Sousa(Agios Pharmaceuticals (United States)), Xiaoyu Zhang(University of Toronto), Eiru Kim(The University of Texas MD Anderson Cancer Center), Rummy Akthar(University of Toronto), Joseph J. Caumanns(University of Toronto), Yuxi Yao(University of Toronto), Nicholas Mikolajewicz(University of Toronto), Catherine Ross(University of Toronto), Kevin R. Brown(University of Toronto), Abdelrahman Abou Zid(University of Toronto), Zi Peng Fan(Agios Pharmaceuticals (United States)), Shirley Hui(University of Toronto), Jordan A. Krall(Agios Pharmaceuticals (United States)), Donald M. Simons(Agios Pharmaceuticals (United States)), Chloe J. Slater(Agios Pharmaceuticals (United States)), Víctor R. De Jesús(Agios Pharmaceuticals (United States)), Lujia Tang(Agios Pharmaceuticals (United States)), Richa Singh(Agios Pharmaceuticals (United States)), Joshua E. Goldford(Agios Pharmaceuticals (United States)), Sarah L. Fordyce Martin(Agios Pharmaceuticals (United States)), Qian Huang(University of Toronto), Elizabeth Francis(University of Toronto), Andrea Habsid(University of Toronto), Ryan Climie(University of Toronto), David Tieu(University of Toronto), Jiarun Wei(University of Toronto), Li Ren(Hospital for Sick Children), Amy H.Y. Tong(University of Toronto), Michael Aregger(University of Toronto), Katherine Chan(University of Toronto), Hong Han(University of Toronto), Xiaowei Wang(University of Toronto), Patricia Mero(University of Toronto), John H. Brumell(University of Toronto), Antonio Finelli(University Health Network), Laurie Ailles(Ontario Institute for Cancer Research), Gary D. Bader(University of Toronto), Gromoslaw A. Smolen(Agios Pharmaceuticals (United States)), Gillian A. Kingsbury(Agios Pharmaceuticals (United States)), Traver Hart(The University of Texas MD Anderson Cancer Center), Charles Kung(Agios Pharmaceuticals (United States)), Jason Moffat(University of Toronto)

Nature

September 23, 2020

10.1038/s41586-020-2746-2

Cited by 473Open Access

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