Post-tuberculosis lung health: perspectives from the First International Symposium

Brian Allwood(Stellenbosch University), Marieke M. van der Zalm(Desmond Tutu HIV Foundation), André F.S. Amaral(Tygerberg Hospital), Anthony Byrne(UNSW Sydney), Sumona Datta(Universidad Peruana Cayetano Heredia), Uzochukwu Egere(Liverpool School of Tropical Medicine), Carlton A. Evans(Universidad Peruana Cayetano Heredia), Denise Evans(University of the Witwatersrand), Diane Gray(University of Cape Town), Graeme Hoddinott(Desmond Tutu HIV Foundation), Olena Ivanova(Ludwig-Maximilians-Universität München), Rupert Jones(University of Plymouth), Goodman Makanda, Florian M. Marx(Stellenbosch University), Jamilah Meghji(Liverpool School of Tropical Medicine), Stellah Mpagama(Central Hospital of Zibo), Jotam G. Pasipanodya(Texas Tech University), Andrea Rachow(German Center for Infection Research), Ingrid Schoeman, Jane Shaw(Stellenbosch University), Cari Stek(University of Cape Town), Sanne van Kampen(Leiden University Medical Center), Dalene von Delft, Naomi F. Walker(University of Liverpool), Robert S. Wallis(Aurum Institute), Kevin Mortimer(Liverpool School of Tropical Medicine)
The International Journal of Tuberculosis and Lung Disease
August 1, 2020
Cited by 255Open Access
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Abstract

International Post-Tuberculosis Symposium (Stellenbosch, South Africa) was held to discuss priorities and gaps in addressing this issue. A barrier to progress has been the varied terminology and nomenclature, so the Delphi process was used to achieve consensus on definitions. Lack of sufficient evidence hampered definitive recommendations in most domains, including prevention and treatment of post-TB lung disease (PTLD), but the discussions clarified the research needed. A consensus was reached on a toolkit for future PTLD measurement and on PTLD patterns to be considered. The importance of extra-pulmonary consequences and progressive impairment throughout the life-course was identified, including TB recurrence and increased mortality. Patient advocates emphasised the need to address the psychological and social impacts post TB and called for clinical guidance. More generally, there is an urgent need for increased awareness and research into post-TB complications.


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