Discovery of <i>N</i>-Arylsulfonyl-Indole-2-Carboxamide Derivatives as Potent, Selective, and Orally Bioavailable Fructose-1,6-Bisphosphatase Inhibitors—Design, Synthesis, <i>In Vivo</i> Glucose Lowering Effects, and X-ray Crystal Complex Analysis
Jie Zhou(Chinese University of Hong Kong), Bailing Xu(Chinese Academy of Medical Sciences & Peking Union Medical College), Rongcui Li(Chinese Academy of Medical Sciences & Peking Union Medical College), Shuainan Liu(Gansu Agricultural University), Hualong Chen(University of Electronic Science and Technology of China), Quan Liu(Dazhou Central Hospital), Xiaoyu Wang(Ministry of Education of the People's Republic of China), Jinping Hu(Chinese Academy of Medical Sciences & Peking Union Medical College), Yan Li(North Sichuan Medical University), Hui Cao(Dalian University of Technology), Jianbo Bie(Chinese Academy of Medical Sciences & Peking Union Medical College), Wenming Ji(Chinese Academy of Medical Sciences & Peking Union Medical College), Zhufang Shen(Jiangnan University)
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