Saliva or Nasopharyngeal Swab Specimens for Detection of SARS-CoV-2

Anne L. Wyllie(Yale University), John Fournier(Yale University), Arnau Casanovas‐Massana(Yale University), Melissa Campbell(Yale University), Maria Tokuyama(Yale University), Pavithra Vijayakumar(Yale University), Joshua L. Warren(Yale University), Bertie Geng(Yale University), M. Catherine Muenker(Yale University), Adam J. Moore(Yale University), Chantal B. F. Vogels(Yale University), Mary E. Petrone(Yale University), Isabel M. Ott(Yale University), Peiwen Lu(Yale University), Arvind Venkataraman(Yale University), Alice Lu-Culligan(Yale University), Jon Klein(Yale University), Rebecca Earnest(Yale University), Michael Simonov(Yale University), Rupak Datta(Yale University), Ryan Handoko(Yale University), Nida Naushad(Yale University), Lorenzo R. Sewanan(Yale University), Jordan Valdez(Yale University), Elizabeth B. White(Yale University), Sarah Lapidus(Yale University), Chaney C. Kalinich(Yale University), Xiaodong Jiang(Yale University), Daniel J. Kim(Yale University), Eriko Kudo(Yale University), Melissa Linehan(Yale University), Tianyang Mao(Yale University), Miyu Moriyama(Yale University), Ji Eun Oh(Yale University), Annsea Park(Yale University), Julio Silva(Yale University), Eric Song(Yale University), Takehiro Takahashi(Yale University), Manabu Taura(Yale University), Orr-El Weizman(Yale University), Patrick Wong(Yale University), Yexin Yang(Yale University), Santos Bermejo(Yale University), Camila D. Odio(Yale New Haven Health System), Saad B. Omer, Charles S. Dela Cruz(Yale University), Shelli Farhadian(Yale University), Richard A. Martinello(Yale University), Akiko Iwasaki(Yale University), Nathan D. Grubaugh(Yale University), Albert I. Ko(Yale University)
New England Journal of Medicine
August 28, 2020
10.1056/nejmc2016359
Cited by 1,048Open Access
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Abstract

In this letter, the investigators report that saliva specimens and nasopharyngeal swab specimens had similar sensitivity in the detection of SARS-CoV-2 RNA in both symptomatic and asymptomatic persons.

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