Natural killer cell immunotypes related to COVID-19 disease severity
Christopher Maucourant(Karolinska University Hospital), Iva Filipovic(Karolinska University Hospital), Andrea Ponzetta(Karolinska University Hospital), Soo Aleman(Karolinska University Hospital), Martin Cornillet(Karolinska University Hospital), Laura Hertwig(Karolinska University Hospital), Benedikt Strunz(Karolinska University Hospital), Antonio Lentini(Karolinska Institutet), Björn Reinius(Karolinska Institutet), Demi Brownlie(Karolinska University Hospital), Angélica Cuapio(Karolinska University Hospital), Eivind Heggernes Ask(Oslo University Hospital), Ryan M. Hull(Science for Life Laboratory), Alvaro Haroun-Izquierdo(Karolinska University Hospital), Marie Schaffer(Karolinska University Hospital), Jonas Klingström(Karolinska University Hospital), Elin Folkesson(Karolinska University Hospital), Marcus Buggert(Karolinska University Hospital), Johan K. Sandberg(Karolinska University Hospital), Lars I. Eriksson(Karolinska University Hospital), Olav Rooyackers(Karolinska University Hospital), Hans‐Gustaf Ljunggren(Karolinska University Hospital), Karl‐Johan Malmberg(Oslo University Hospital), Jakob Michaëlsson(Karolinska University Hospital), Nicole Marquardt(Karolinska University Hospital), Quirin Hammer(Karolinska University Hospital), Kristoffer Strålin(Karolinska University Hospital), Niklas K. Björkström(Karolinska University Hospital), The Karolinska COVID-19 Study Group
Cited by 511Open Access
Abstract
NK cells was observed across COVID-19 disease states, driven by a defined protein-protein interaction network of inflammatory soluble factors. This study provides a detailed map of the NK cell activation landscape in COVID-19 disease.
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