Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2′3′-cGAMP
Zhen Zhao(QIMR Berghofer Medical Research Institute), Zhengfan Jiang(Peking University), Zhixing Ma(Peking University), Xiao‐Dong Su(Peking University), Yukun Guan(Peking University), Bo Wang(Peking University)
Cited by 310
Related Papers
Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy
|Cell Research|2020|987
Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses
|Immunity|2018|809