Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas

Abstract

(Cell Reports 28, 1370–1384.e1–e5; July 30, 2019) In the originally published version of this article, The Cancer Genome Atlas (TCGA) Network was listed as an author because all of the analyses were based on TCGA data. However, because this paper was not officially authorized by the TCGA Network, we have now removed The Cancer Genome Atlas Network as an author. The authors regret this error. Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome AtlasDonehower et al.Cell ReportsJuly 30, 2019In BriefDonehower et al. performed a comprehensive analysis of the effects of TP53 gene mutation in 32 cancer types and 10,225 patients from The Cancer Genome Atlas (TCGA). Data synthesized from five different analysis platforms show how mutant TP53 increases genomic instability and induces major pathway signaling changes in cancer cells. Full-Text PDF Open Access