SYNTHESIS OF NOVEL C-4 DISUBSTITUTED β-LACTAMS THROUGH STAUDINGER CYCLOADDITION REACTION

Robert Rodriguez, Anjali Nambiar, Ram Naresh Yadav, Bimal Krishna Banik
ScholarWorks @ UTRGV (The University of Texas Rio Grande Valley)
January 1, 2014
Cited by 0Open Access
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Abstract

Synthesis of novel C-4 disubstituted beta-lactam that has N-methyl pyrrole system has been achieved through Staudinger cycloaddition reaction of acid chloride and imine. Interestingly, this reaction has produced a single stereoisomer.

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