SARS-CoV-2: characteristics and current advances in research

Yicheng Yang(Chinese Academy of Medical Sciences & Peking Union Medical College), Zhiqiang Xiao(Zhengzhou University), Kaiyan Ye(Southern Medical University), Xiaoen He(Southern Medical University), Bo Sun(Chinese Academy of Medical Sciences & Peking Union Medical College), Zhiran Qin(Southern Medical University), Jianghai Yu(Southern Medical University), Jinxiu Yao, Qinghua Wu(Southern Medical University), Zhang Bao(Southern Medical University), Wei Zhao(Southern Medical University)
Virology Journal
July 29, 2020
10.1186/s12985-020-01369-z
Cited by 160Open Access
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Abstract

Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has spread rapidly across the world and become an international public health emergency. Both SARS-CoV-2 and SARS-CoV belong to subfamily Coronavirinae in the family Coronaviridae of the order Nidovirales and they are classified as the SARS-like species while belong to different cluster. Besides, viral structure, epidemiology characteristics and pathological characteristics are also different. We present a comprehensive survey of the latest coronavirus-SARS-CoV-2-from investigating its origin and evolution alongside SARS-CoV. Meanwhile, pathogenesis, cardiovascular disease in COVID-19 patients, myocardial injury and venous thromboembolism induced by SARS-CoV-2 as well as the treatment methods are summarized in this review.

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