Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model
Chun Chen(Emory University), Eun Hee Ahn(Emory University), Seong Su Kang(Emory University), Xia Liu(Emory University), Ashfaqul Alam(University of Kentucky), Keqiang Ye(Emory University)
Cited by 197Open Access
Abstract
antagonizes the C/EBPβ/AEP axis, mitigating gut leakage and oxidative stress. Our findings support the hypothesis that C/EBPβ/AEP signaling is activated by gut dysbiosis, implicated in AD pathologies in the gut.