A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

H. J. Yang; Wei Wang; Zimin Chen; Shuaiyao Lu; Fanli Yang; Zhenfei Bi; Linlin Bao; Fei Mo; Xue Li; Yong Huang; Weiqi Hong; Yun Yang; Yuan Zhao; Fei Ye; Sheng Lin; Wei Deng; Hua Chen; Lei Hong; Ziqi Zhang; Min Luo; Hong Gao; Yue Zheng; Yanqiu Gong; Xiaohua Jiang; Yanfeng Xu; Qi Lv; Dan Li; Manni Wang; Fengdi Li; Shunyi Wang; Guanpeng Wang; Pin Yü; Yajin Qu; Li Yang; Hongxin Deng; Aiping Tong; Jiong Li; Zhenling Wang; Jinliang Yang; Guobo Shen; Zhiwei Zhao; Yuhua Li; Jingwen Luo; Hongqi Liu; Wenhai Yu; Mengli Yang; Jingwen Xu; Junbin Wang; Haiyan Li; Haixuan Wang; Dexuan Kuang; Panpan Lin; Zhengtao Hu; Wei Guo; Wei Cheng; Yanlin He; Xiangrong Song; Chong Chen; Zhihong Xue; Shaohua Yao; Lu Chen; Xuelei Ma; Siyuan Chen; Maling Gou; Weijin Huang; Youchun Wang; Changfa Fan; Zhixin Tian; Ming Shi; Fu‐Sheng Wang; Lunzhi Dai; Min Wu; Gen Li; Guangyu Wang; Yong Peng; Zhiyong Qian; Canhua Huang; Johnson Yiu‐Nam Lau; Zhenglin Yang; Yuquan Wei; Xiaobo Cen; Xiaozhong Peng; Chuan Qin; Kang Zhang; Guangwen Lu; Xiawei Wei

doi:10.1038/s41586-020-2599-8

A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

H. J. Yang(Sichuan University), Wei Wang(Sichuan University), Zimin Chen(Sichuan University), Shuaiyao Lu(Chinese Academy of Medical Sciences & Peking Union Medical College), Fanli Yang(Sichuan University), Zhenfei Bi(Sichuan University), Linlin Bao(Chinese Academy of Medical Sciences & Peking Union Medical College), Fei Mo(Sichuan University), Xue Li(Sichuan University), Yong Huang(Sichuan University), Weiqi Hong(Sichuan University), Yun Yang(Chinese Academy of Medical Sciences & Peking Union Medical College), Yuan Zhao(Chinese Academy of Medical Sciences & Peking Union Medical College), Fei Ye(Sichuan University), Sheng Lin(Sichuan University), Wei Deng(Chinese Academy of Medical Sciences & Peking Union Medical College), Hua Chen(Sichuan University), Lei Hong(Sichuan University), Ziqi Zhang(Sichuan University), Min Luo(Sichuan University), Hong Gao(Chinese Academy of Medical Sciences & Peking Union Medical College), Yue Zheng(Sichuan University), Yanqiu Gong(Sichuan University), Xiaohua Jiang(Sichuan University), Yanfeng Xu(Chinese Academy of Medical Sciences & Peking Union Medical College), Qi Lv(Chinese Academy of Medical Sciences & Peking Union Medical College), Dan Li(Sichuan University), Manni Wang(Sichuan University), Fengdi Li(Chinese Academy of Medical Sciences & Peking Union Medical College), Shunyi Wang(Chinese Academy of Medical Sciences & Peking Union Medical College), Guanpeng Wang(Chinese Academy of Medical Sciences & Peking Union Medical College), Pin Yü(Chinese Academy of Medical Sciences & Peking Union Medical College), Yajin Qu(Chinese Academy of Medical Sciences & Peking Union Medical College), Li Yang(Sichuan University), Hongxin Deng(Sichuan University), Aiping Tong(Sichuan University), Jiong Li(Sichuan University), Zhenling Wang(Sichuan University), Jinliang Yang(Sichuan University), Guobo Shen(Sichuan University), Zhiwei Zhao(Sichuan University), Yuhua Li(National Institutes for Food and Drug Control), Jingwen Luo(Sichuan University), Hongqi Liu(Chinese Academy of Medical Sciences & Peking Union Medical College), Wenhai Yu(Chinese Academy of Medical Sciences & Peking Union Medical College), Mengli Yang(Chinese Academy of Medical Sciences & Peking Union Medical College), Jingwen Xu(Chinese Academy of Medical Sciences & Peking Union Medical College), Junbin Wang(Chinese Academy of Medical Sciences & Peking Union Medical College), Haiyan Li(Chinese Academy of Medical Sciences & Peking Union Medical College), Haixuan Wang(Chinese Academy of Medical Sciences & Peking Union Medical College), Dexuan Kuang(Chinese Academy of Medical Sciences & Peking Union Medical College), Panpan Lin(Sichuan University), Zhengtao Hu(Sichuan University), Wei Guo(Sichuan University), Wei Cheng(Sichuan University), Yanlin He(Sichuan University), Xiangrong Song(Sichuan University), Chong Chen(Sichuan University), Zhihong Xue(Sichuan University), Shaohua Yao(Sichuan University), Lu Chen(Sichuan University), Xuelei Ma(Sichuan University), Siyuan Chen(Sichuan University), Maling Gou(Sichuan University), Weijin Huang(National Institutes for Food and Drug Control), Youchun Wang(National Institutes for Food and Drug Control), Changfa Fan(National Institutes for Food and Drug Control), Zhixin Tian(Tongji University), Ming Shi, Fu‐Sheng Wang, Lunzhi Dai(Sichuan University), Min Wu(Sichuan University), Gen Li(Macau University of Science and Technology), Guangyu Wang(Chinese Academy of Medical Sciences & Peking Union Medical College), Yong Peng(Sichuan University), Zhiyong Qian(Sichuan University), Canhua Huang(Sichuan University), Johnson Yiu‐Nam Lau(Hong Kong Polytechnic University), Zhenglin Yang(University of Electronic Science and Technology of China), Yuquan Wei(Sichuan University), Xiaobo Cen(Sichuan University), Xiaozhong Peng(Chinese Academy of Medical Sciences & Peking Union Medical College), Chuan Qin(Chinese Academy of Medical Sciences & Peking Union Medical College), Kang Zhang(Macau University of Science and Technology), Guangwen Lu(Sichuan University), Xiawei Wei(Sichuan University)

Nature

July 29, 2020

10.1038/s41586-020-2599-8

Cited by 845Open Access

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