TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress

Kailiang Zhou; Zhilong Zheng; Yao Li; Wen Han; Jing Zhang; Yuqin Mao; Huanwen Chen; Wanying Zhang; Mi Liu; Ling Xie; Hongyu Zhang; Huazi Xu; Jian Xiao

doi:10.7150/thno.46566

TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress

Kailiang Zhou(Wenzhou Medical University), Zhilong Zheng(Wenzhou Medical University), Yao Li(Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University), Wen Han(Wenzhou Medical University), Jing Zhang(Wenzhou Medical University), Yuqin Mao(Wenzhou Medical University), Huanwen Chen(University of Maryland, Baltimore), Wanying Zhang(Wenzhou Medical University), Mi Liu(Wenzhou Medical University), Ling Xie(Wenzhou Medical University), Hongyu Zhang(Wenzhou Medical University), Huazi Xu(Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University), Jian Xiao(Wenzhou Medical University)

Theranostics

January 1, 2020

10.7150/thno.46566

Cited by 155Open Access

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Abstract

TFE3 is an important regulator in ROS-mediated autophagy dysfunction following SCI, and TFE3 may serve as a promising target for developing treatments for SCI.

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