Förster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents
Luling Wu(Shanghai Normal University), Chusen Huang(Shanghai Normal University), Ben P. Emery(University of Bath), Adam C. Sedgwick(The University of Texas at Austin), Steven D. Bull(University of Bath), Xiao‐Peng He(East China University of Science and Technology), He Tian(East China University of Science and Technology), Juyoung Yoon(Ewha Womans University), Jonathan L. Sessler(The University of Texas at Austin), Tony D. James(Shanghai Normal University)
Cited by 977Open Access
Abstract
In this tutorial review, we will explore recent advances in the construction and application of Förster resonance energy transfer (FRET)-based small-molecule fluorescent probes. The advantages of FRET-based fluorescent probes include: a large Stokes shift, ratiometric sensing and dual/multi-analyte responsive systems. We discuss the underlying energy donor-acceptor dye combinations and emphasise their applications for the detection or imaging of cations, anions, small neutral molecules, biomacromolecules, cellular microenvionments and dual/multi-analyte responsive systems.
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