Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
Jinxin Che(Pharmaceutical Biotechnology (Czechia)), Xiaowu Dong(Second Affiliated Hospital of Zhejiang University), Bingxue Qu(Zhejiang University), Jian Gao(Hebei Medical University), Xiaobei Hu(Chinese Academy of Sciences), Jianjun Zhang(Shanghai Jiao Tong University), Mengmeng Zhang(Zhongkai University of Agriculture and Engineering), Huazhou Ying(Zhejiang University), Yubo Zhou(University of Science and Technology of China), Feng Huang(Zhejiang University), Anhui Gao(Chinese Academy of Sciences), Jia Li(Shanghai Institute of Materia Medica), Yongzhou Hu(Zhejiang University), Gaoya Xu(Shanghai Institute of Materia Medica), Binhui Chen(Zhejiang University)
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