Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys

Yuji Nagai; Naohisa Miyakawa; Hiroyuki Takuwa; Yukiko Hori; Kei Oyama; Bin Ji; Manami Takahashi; Xi‐Ping Huang; Samuel T. Slocum; Jeffrey F. DiBerto; Yan Xiong; Takuya Urushihata; Toshiyuki Hirabayashi; Atsushi Fujimoto; Koki Mimura; Justin G. English; Jing Liu; Ken‐ichi Inoue; Katsushi Kumata; Chie Seki; Maiko Ono; Masafumi Shimojo; Ming-Rong Zhang; Yutaka Tomita; Jin Nakahara; Tetsuya Suhara; Masahiko Takada; Makoto Higuchi; Jian Jin; Bryan L. Roth; Takafumi Minamimoto

doi:10.1038/s41593-020-0661-3

Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys

Yuji Nagai(National Institutes for Quantum Science and Technology), Naohisa Miyakawa(National Institutes for Quantum Science and Technology), Hiroyuki Takuwa(National Institutes for Quantum Science and Technology), Yukiko Hori(National Institutes for Quantum Science and Technology), Kei Oyama(National Institutes for Quantum Science and Technology), Bin Ji(National Institutes for Quantum Science and Technology), Manami Takahashi(National Institutes for Quantum Science and Technology), Xi‐Ping Huang(University of North Carolina at Chapel Hill), Samuel T. Slocum(University of North Carolina at Chapel Hill), Jeffrey F. DiBerto(University of North Carolina at Chapel Hill), Yan Xiong(Icahn School of Medicine at Mount Sinai), Takuya Urushihata(National Institutes for Quantum Science and Technology), Toshiyuki Hirabayashi(National Institutes for Quantum Science and Technology), Atsushi Fujimoto(National Institutes for Quantum Science and Technology), Koki Mimura(National Institutes for Quantum Science and Technology), Justin G. English(University of North Carolina at Chapel Hill), Jing Liu(Icahn School of Medicine at Mount Sinai), Ken‐ichi Inoue(Kyoto University), Katsushi Kumata(National Institutes for Quantum Science and Technology), Chie Seki(National Institutes for Quantum Science and Technology), Maiko Ono(National Institutes for Quantum Science and Technology), Masafumi Shimojo(National Institutes for Quantum Science and Technology), Ming-Rong Zhang(National Institutes for Quantum Science and Technology), Yutaka Tomita(Keio University), Jin Nakahara(Keio University), Tetsuya Suhara(National Institutes for Quantum Science and Technology), Masahiko Takada(Kyoto University), Makoto Higuchi(National Institutes for Quantum Science and Technology), Jian Jin(Icahn School of Medicine at Mount Sinai), Bryan L. Roth(University of North Carolina at Chapel Hill), Takafumi Minamimoto(National Institutes for Quantum Science and Technology)

Nature Neuroscience

July 6, 2020

10.1038/s41593-020-0661-3

Cited by 425

Abstract

Related Papers

No related papers found

Powered by citation graph analysis