Perceived versus proven SARS-CoV-2-specific immune responses in health-care professionals
Georg M. N. Behrens(Medizinische Hochschule Hannover), Anne Cossmann(Medizinische Hochschule Hannover), Metodi V. Stankov(Medizinische Hochschule Hannover), Torsten Witte(Medizinische Hochschule Hannover), Diana Ernst(Medizinische Hochschule Hannover), Christine Happle(Medizinische Hochschule Hannover), Alexandra Dopfer‐Jablonka(Medizinische Hochschule Hannover)
Cited by 81Open Access
Abstract
There have been concerns about high rates of thus far undiagnosed SARS-CoV-2 infections in the health-care system. The COVID-19 Contact (CoCo) Study follows 217 frontline health-care professionals at a university hospital with weekly SARS-CoV-2-specific serology (IgA/IgG). Study participants estimated their personal likelihood of having had a SARS-CoV-2 infection with a mean of 21% [median 15%, interquartile range (IQR) 5-30%]. In contrast, anti-SARS-CoV-2 IgG prevalence was about 1-2% at baseline. Regular anti-SARS-CoV-2 IgG testing of health-care professionals may aid in directing resources for protective measures and care of COVID-19 patients in the long run.
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