The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate excretion
Kazi Mirajul Hoque(University of Maryland, Baltimore), Owen M. Woodward(University of Maryland, Baltimore)
Cited by 146
Related Papers
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
|Proceedings of the National Academy of Sciences|2009|694
Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele
|Human Molecular Genetics|2011|143
Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules
|Proceedings of the National Academy of Sciences|2013|109
ABCG transporters and disease
|FEBS Journal|2011|74
The Epac1 Signaling Pathway Regulates Cl− Secretion via Modulation of Apical KCNN4c Channels in Diarrhea
|Journal of Biological Chemistry|2013|29