COVID‐19 associated pulmonary aspergillosis

Philipp Koehler(University of Cologne), Oliver A. Cornely(TH Köln - University of Applied Sciences), Bernd W. Böttiger(University of Cologne), Fabian Dusse(University of Cologne), Dennis A. Eichenauer(University of Cologne), Frieder Fuchs(University of Cologne), Michael Hallek(University of Cologne), Norma Jung(University of Cologne), Florian Klein(University of Cologne), Thorsten Persigehl(University of Cologne), Jan Rybniker(University of Cologne), Matthias Kochanek(University of Cologne), Boris Böll(University of Cologne), Alexander Shimabukuro‐Vornhagen(University of Cologne)
Mycoses
April 27, 2020
10.1111/myc.13096
Cited by 549Open Access
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Abstract

OBJECTIVES: Patients with acute respiratory distress syndrome (ARDS) due to viral infection are at risk for secondary complications like invasive aspergillosis. Our study evaluates coronavirus disease 19 (COVID-19) associated invasive aspergillosis at a single centre in Cologne, Germany. METHODS: A retrospective chart review of all patients with COVID-19 associated ARDS admitted to the medical or surgical intensive care unit at the University Hospital of Cologne, Cologne, Germany. RESULTS: COVID-19 associated invasive pulmonary aspergillosis was found in five of 19 consecutive critically ill patients with moderate to severe ARDS. CONCLUSION: Clinicians caring for patients with ARDS due to COVID-19 should consider invasive pulmonary aspergillosis and subject respiratory samples to comprehensive analysis to detect co-infection.

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