Early Virus Clearance and Delayed Antibody Response in a Case of Coronavirus Disease 2019 (COVID-19) With a History of Coinfection With Human Immunodeficiency Virus Type 1 and Hepatitis C Virus
Juanjuan Zhao(Shenzhen Third People’s Hospital), Xuejiao Liao(Shenzhen Third People’s Hospital), Haiyan Wang(Shenzhen Third People’s Hospital), Lanlan Wei(Shenzhen Third People’s Hospital), Mingzhao Xing(Southern University of Science and Technology), Lei Liu(Southern University of Science and Technology), Zheng Zhang(Southern University of Science and Technology)
Cited by 118Open Access
Abstract
The effect of host immune status on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains unknown. Here, we report the first case of coronavirus disease 2019 (COVID-19) with human immunodeficiency virus type 1 (HIV-1)/hepatitis C virus coinfection, who showed a persistently negative SARS-CoV-2 RNA test but delayed antibody response in the plasma. This case highlights the influence of HIV-1-induced immune dysfunction on early SARS-CoV-2 clearance.
Related Papers
No related papers found
Powered by citation graph analysis