A novel triptolide derivative ZT01 exerts anti-inflammatory effects by targeting TAK1 to prevent macrophage polarization into pro-inflammatory phenotype

Junmin Fu(Chinese Academy of Medical Sciences & Peking Union Medical College), Tiantai Zhang(Chinese Academy of Medical Sciences & Peking Union Medical College), Shuai Shao(Chinese Academy of Medical Sciences & Peking Union Medical College), Chengjuan Chen(Chinese Academy of Medical Sciences & Peking Union Medical College), Yu Zhou(Chinese Academy of Medical Sciences & Peking Union Medical College), Lei Wu(Southeast University), Dongming Zhang(Heilongjiang Bayi Agricultural University), Gaona Shi(Chinese Academy of Medical Sciences & Peking Union Medical College), Min Hu(Nanchang University), Yingda Zang(Chinese Academy of Medical Sciences & Peking Union Medical College)
Biomedicine & Pharmacotherapy
March 11, 2020
10.1016/j.biopha.2020.110084
Cited by 24

Related Papers

Origins and functional impact of copy number variation in the human genome
|Nature|2009|2k
Role of COX-2 in epithelial–stromal cell interactions and progression of ductal carcinoma in situ of the breast
|Proceedings of the National Academy of Sciences|2009|202
Molecular Imaging of Atherosclerotic Plaques Using a Human Antibody Against the Extra-Domain B of Fibronectin
|Circulation Research|2004|114
Divanillyl sulfone suppresses NLRP3 inflammasome activation via inducing mitophagy to ameliorate chronic neuropathic pain in mice
|Journal of Neuroinflammation|2021|109
Hepatoprotective Sesquiterpene Glycosides from <i>Sarcandra </i><i>g</i><i>labra</i>
|Journal of Natural Products|2006|98