Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
Jia Liu(Chinese Academy of Sciences), Ruiyuan Cao(National Institutes for Food and Drug Control), Mingyue Xu(Chinese Academy of Sciences), Xi Wang(Chinese Academy of Sciences), Huanyu Zhang(Chinese Academy of Sciences), Hengrui Hu(Chinese Academy of Sciences), Yufeng Li(Chinese Academy of Sciences), Zhìhóng Hú(Chinese Academy of Sciences), Wu Zhong(National Institutes for Food and Drug Control), Manli Wang(Chinese Academy of Sciences)
Cited by 2,182Open Access
Abstract
The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2/2019-nCoV) poses a serious threat to global public health and local economies. As of March 3, 2020, over 80,000 cases have been confirmed in China, including 2946 deaths as well as over 10,566 confirmed cases in 72 other countries. Such huge numbers of infected and dead people call for an urgent demand of effective, available, and affordable drugs to control and diminish the epidemic.
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